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TranscriptomicsSingle-cell multiome analysis of human in vitro activated CD4 T cells
This study looks at the ATAC+RNA profiles of human CD4 T cells under bioreactor-like conditions as ACT. Cells were stimulated toward Th1,Th2,Treg and Th17 under anti-CD3/28 activation, and profiled on day 5.
ORGANISM(S): Homo sapiens 
2024-01-31 | E-MTAB-13711 | biostudies-arrayexpress
ProteomicsIdentification of potential plasma biomarkers for abdominal aortic aneurysm using tandem mass tag quantitative proteomics
Plasma biomarkers that identify abdominal aortic aneurysm (AAA) rupture risk would greatly assist in stratifying patients with small aneurysms. Identification of such biomarkers has hitherto been unsuccessful over a range of studies using different methods. The present study used an alternative prot...
ORGANISM(S): Homo sapiens (Human) 
2018-10-22 | PXD011309 | Pride
Plasma proteomics  immunodepletion  tandem mass tags  tmt  abdominal aortic aneurysm  cardiovascular diseases 
TranscriptomicsImmune activated B cells are dominant in Prostate cancer - BCR sequencing
B cell receptor (BCR)-sequencing from 3 donors with prostate cancer. The sources are Peripheral blood B cells (P), tumour draining lymph nodes (S) and non-draining lymph nodes (N).
ORGANISM(S): Homo sapiens 
2023-01-01 | E-MTAB-11862 | biostudies-arrayexpress
TranscriptomicsOverexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment
This experiment shows that the in vitro effect of 4u8c on Th2 cells can be rescued using XBP1s overexpression
ORGANISM(S): Mus musculus 
2018-10-06 | E-MTAB-7104 | biostudies-arrayexpress
UnknownPatients With Proneural Glioblastoma May Derive Overall Survival Benefit From the Addition of Bevacizumab to First-Line Radiotherapy and Temozolomide: Retrospective Analysis of the AVAglio Trial.
Not available
S-EPMC5015426 | biostudies-literature
TranscriptomicsSingle-cell multiome analysis of human tonsil B cells
B cells from tonsils of human donors were extracted for combined RNAseq+ATACseq from the same cell. One sample was prepared separately ("old") and is of lower quality, but still included. It primarily holds ATACseq information.
ORGANISM(S): Homo sapiens 
2023-04-13 | E-MTAB-12632 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA+ATAC sequencing of human CRL-1459 colonic fibroblasts
The 10x multiome (RNA+ATAC) kit was applied to CRL-1459 cells in culture at passage 10 and 15
ORGANISM(S): Homo sapiens 
2024-07-13 | E-MTAB-14220 | biostudies-arrayexpress
TranscriptomicsThe fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes
Background/Objectives: Obese subjects have increased number of enlarged fat cells which are reduced in size but not number in post-obesity. We performed DNA methylation profiling in fat cells with the aim of identifying differentially methylated DNA sites (DMS) linked to adipose hyperplasia (many sm...
ORGANISM(S): Homo sapiens 
2015-05-06 | E-GEOD-58622 | biostudies-arrayexpress
TranscriptomicsThe cross-talk between prostate cancer cells and myeloid cells to prime cancer metastasis
RNA-seq of co-cultured and monocultured PC-3 and U937 cell lines. Cells were separated by FACS. The PC-3 uptake of U937 material was measured by staining the U937 with DiD and CFSE. Samples described as 4samp_* were a first sequencing trial of the same samples.
ORGANISM(S): Homo sapiens 
2022-11-30 | E-MTAB-11378 | biostudies-arrayexpress
UnknownEstimating the marginal cost of a life year in Sweden's public healthcare sector.
Not available
S-EPMC6602994 | biostudies-literature
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