Metabolic reprogramming fuels cancer cell metastasis and remodels the immunosuppressive tumor microenvironment (TME). We report here that a circRNA, circPETH, packaged by extracellular vesicles (EVs) from tumor-associated macrophages (TAMs) to hepatocellular carcinoma (HCC) cells, facilitates glycol...
Mutations in repulsive guidance molecule c (RGMc) / hemojuvelin (HJV) cause juvenile hemochromatosis, an aggravated iron overload disorder that presents early in life. Patients with juvenile hemochromatosis, and RGMc knockout mice, have diminished expression of the key iron-regulatory peptide, hepc...
We identified phosphorylated SEPs in Hep3B cells. ACN precipitation, thermo precipitation and HCl precipitation were used to enrich SEPs. Three materials (nmTiO2, umTiO2, IMAC) were used to enrich phosphorylated peptides.