Sort   by:  
 Page size 
MetabolomicsMetabolic characterization of the natural progression of chronic hepatitis B (Lipid assays)
Background: Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive liver diseases. The confinement of HBV replication to the liver, which also acts as the central hub for metabolic and nutritional regulation, e...
2016-06-06 | MTBLS279 | MetaboLights
MetabolomicsMulti-omic Molecular Characterization and Diagnostic Biomarkers for Occult Hepatitis B Infection and HBsAg-Positive Hepatitis B Infection

BACKGROUND: The pathological and physiological characteristics between HBsAg-positive HBV infection and occult hepatitis B infection (OBI) are currently unclear. This study aimed to explore the immune microenvironment in the peripheral circulation of OBI patients through integration of proteomic ...

2024-11-05 | MTBLS11406 | MetaboLights
MetabolomicsMetabolic characterization of the natural progression of chronic hepatitis B (Biogenic amine and Acyl-carnitine assays)
Background: Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive liver diseases. The confinement of HBV replication to the liver, which also acts as the central hub for metabolic and nutritional regulation, e...
2016-06-06 | MTBLS280 | MetaboLights
MetabolomicsMetabolic characterization of the natural progression of chronic hepatitis B (Oxylipin assay)
Background: Worldwide, over 350 million people are chronically infected with the hepatitis B virus (HBV) and are at increased risk of developing progressive liver diseases. The confinement of HBV replication to the liver, which also acts as the central hub for metabolic and nutritional regulation, e...
2016-06-06 | MTBLS253 | MetaboLights
ProteomicsGeneration and utilization of a monoclonal antibody against hepatitis B virus core protein for a comprehensive interactome analysis
Hepatitis B virus (HBV) core antigen (HBc) is a structural protein that forms the viral nucleocapsid and is involved in various steps of the viral replication cycle, but its role in the pathogenesis of HBV infection is still elusive. In this study, we generated a mouse monoclonal antibody against HB...
ORGANISM(S): Homo Sapiens (human) 
2023-02-21 | PXD036961 | JPOST Repository
ProteomicsLabel-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line
Hepatitis B virus (HBV) infection is a major health problem worldwide. Recent evidence suggests that various viruses can manipulate the infection process by secretion of specific viral and cellular components into exosomes, small nanometer-sized (30-150 nm) vesicles secreted from various cells. Howe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080718 | MassIVE
TranscriptomicsGene expression profiling of hepatitis B- and hepatitis C-related hepatocellular carcinoma using graphical Gaussian modeling
Gene expression profiling of hepatocellular carcinoma (HCC) and background liver has been studied extensively; however, the relationship between the gene expression profiles of different lesions has not been assessed. We examined the expression profiles of 34 HCC specimens (17 hepatitis B virus [HBV...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-GEOD-44074 | biostudies-arrayexpress
ProteomicsHuh-7 exosomes and HBV
Hepatitis B virus (HBV) infection could cause hepatitis, liver cirrhosis and hepatocellular carcinoma. HBV-mediated pathogenesis is only partially understood, but X protein (HBx) reportedly possesses oncogenic potential. Exosomes are small membrane vesicles with diverse functions released by various...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080794 | MassIVE
TranscriptomicsB-Cell Gene Signature with Massive Intrahepatic Production of Antibodies to Hepatitis B Core Antigen in HBV-Associated Acute Liver Failure
Hepatitis B virus (HBV)-associated acute liver failure (ALF) is a dramatic clinical syndrome due to a sudden loss of hepatic cells leading to multiorgan failure. The mechanisms whereby HBV induces ALF are unknown. We used gene expression profiling to establish a molecular definition of hepatitis B v...
ORGANISM(S): Homo sapiens 
2010-04-26 | E-GEOD-14668 | biostudies-arrayexpress
MetabolomicsEngineered Oncolytic VSV Enhances Tumor Killing in HBV-Positive HCC
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, with chronic hepatitis B virus (HBV) infection being a major contributor to its development. Despite this, effective treatment for HBV-associated HCC remains a significant challenge. In this study, we combined the s...
2025-07-17 | MTBLS12196 | MetaboLights
Sort   by:  
 Page size