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ProteomicsTranscriptomic and Proteomic Response of HC-04 to hepatocyte growth factor (HGF)
The routine study of human malaria liver-stage biology in vitro is hampered by low infection efficiency of human hepatocellular carcinoma (HCC) lines (<0.1%), poor understanding of steady-state HCC biology, and lack of appropriate tools for trace sample analysis. HC-04 is the only HCC that supports ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079959 | MassIVE
TranscriptomicsTranscription profiling of human lymphatic endothelial cells treated with hepatocyte Growth Factor (HGF)
Effect of Hepatocyte Growth Factor (HGF) on lymphatic endothelial cells.
ORGANISM(S): Homo sapiens 
2005-02-01 | E-MEXP-256 | biostudies-arrayexpress
TranscriptomicsExpression array analysis of the hepatocyte growth factor (HGF) invasive program
HGF stimulates mitogenesis, motogenesis and morphogenesis in most epithelial target cells. Selective inhibition of HGF signaling blocks spontaneous metastasis, but not primary tumor growth, in the prostate adenocarcinoma derived PC3M cell xenograft model. To identify the HGF activated genes and path...
ORGANISM(S): Homo sapiens 
2015-08-25 | E-GEOD-71404 | biostudies-arrayexpress
MetabolomicsBile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (untargeted metabolome profile assay)

BACKGROUND: Intestinal bacteria are known to regulate the bile acid (BA) homeostasis via intestinal biotransformation of BAs and stimulating the expression of fibroblast growth factor 19 through intestinal nuclear farnesoid X receptor (FXR). On the other hand, BAs directly regula...

2017-11-23 | MTBLS545 | MetaboLights
MetabolomicsBile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (targeted bile acid analysis assay)

BACKGROUND: Intestinal bacteria are known to regulate the bile acid (BA) homeostasis via intestinal biotransformation of BAs and stimulating the expression of fibroblast growth factor 19 through intestinal nuclear farnesoid X receptor (FXR). On the other hand, BAs directly regula...

2017-11-23 | MTBLS547 | MetaboLights
MetabolomicsBile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (targeted free fatty acid analysis assay)

BACKGROUND: Intestinal bacteria are known to regulate the bile acid (BA) homeostasis via intestinal biotransformation of BAs and stimulating the expression of fibroblast growth factor 19 through intestinal nuclear farnesoid X receptor (FXR). On the other hand, BAs directly regula...

2017-11-23 | MTBLS548 | MetaboLights
MetabolomicsBile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (targeted short chain fatty acid analysis assay)

BACKGROUND: Intestinal bacteria are known to regulate the bile acid (BA) homeostasis via intestinal biotransformation of BAs and stimulating the expression of fibroblast growth factor 19 through intestinal nuclear farnesoid X receptor (FXR). On the other hand, BAs directly regula...

2017-11-23 | MTBLS546 | MetaboLights
ProteomicsTranscriptomic and Proteomic Response of HC-04 to hepatocyte growth factor (HGF)
The routine study of human malaria liver-stage biology in vitro is hampered by low infection efficiency of human hepatocellular carcinoma (HCC) lines (<0.1%), poor understanding of steady-state HCC biology, and lack of appropriate tools for trace sample analysis. HC-04 is the only HCC that supports ...
ORGANISM(S): Homo sapiens (Human) 
2014-02-17 | PXD000682 | Pride
Host-pathogen interaction Mass spectrometry Emt Human hepatocellular carcinoma Transcriptomics Malaria Proteomics 
TranscriptomicsIdentifying Hepatocyte Growth Factor dose response functions in Madin-Darby Canine Kidney Epithelial Cells
Two biological replicates of Madin-Darby Canine Kidney Epithelial Cells grown as 3D cysts in Collagen Type I (7 days old) were exposed to six different concentrations of Hepatocyte Growth Factor (HGF) (0, 1.03, 2.07, 4.15, 8.33 and 16.67 ng/ml). Total RNA was isolated from the cysts after 12 hours o...
ORGANISM(S): Canis lupus familiaris 
2016-01-17 | E-MTAB-4959 | biostudies-arrayexpress
TranscriptomicsComparison of Hepatocyte nuclear factor 4 alpha developmental and temporal knockout mice
The goal of this experiment was to distinguish those genes regulated following acute HNF4alpha depletion compared to a developmental knockout model where gene compensation may comfound results. Expression profile of livers from 8 week old male Hnf4alpha Flox mice that express either albumin cre or t...
ORGANISM(S): Mus musculus 
2012-02-21 | E-GEOD-34581 | biostudies-arrayexpress
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