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GenomicsHepatokine ORM2 suppresses pathological ferritinophagy to prevent acute tissue injury
Hepatokine ORM2 suppresses pathological ferritinophagy to prevent acute tissue injury
PRJNA1162917 | ENA
Genomics
Hepatokine
PRJNA1254202 | ENA
TranscriptomicsHepatokine ORM2 suppresses pathological ferritinophagy to prevent acute tissue injury
Acute tissue injuries trigger rapid cellular damage, but cell-intrinsic protective programs attenuate pathology through regulatory axes. Here, we demonstrate that Orosomucoid 2 (ORM2), a hepatokine, is significantly upregulated during drug-induced acute liver injury. Knock out Orm2 exacerbates liver...
ORGANISM(S): Mus musculus 
2024-09-22 | GSE277619 | GEO
GenomicsMapping the molecular signatures of diet-induced NASH and its regulation by the hepatokine Tsukushi
Mapping the molecular signatures of diet-induced NASH and its regulation by the hepatokine Tsukushi
PRJNA488808 | ENA
UnknownThe hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis.
Not available
S-EPMC6693835 | biostudies-literature
UnknownDeep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control.
Not available
S-EPMC8913628 | biostudies-literature
UnknownThe bile acid induced hepatokine orosomucoid suppresses adipocyte differentiation.
Not available
S-EPMC7785631 | biostudies-literature
UnknownHepatokine ITIH3 protects against hepatic steatosis by downregulating mitochondrial bioenergetics and de novo lipogenesis.
Not available
S-EPMC11059128 | biostudies-literature
UnknownMapping the molecular signatures of diet-induced NASH and its regulation by the hepatokine Tsukushi.
Not available
S-EPMC6358550 | biostudies-literature
UnknownA hepatokine derived from the ER protein CREBH promotes triglyceride metabolism by stimulating lipoprotein lipase activity.
Not available
S-EPMC10080946 | biostudies-literature
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