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TranscriptomicsGenome-Wide Expression Profiling of human tumor-infiltrating microglia/macrophages
Microglia isolated from glioma patients gain anti-tumor activities upon poly (I:C) stimulation. Expression profiles of human tumor-infiltrating microglia/macrophages before (untreated) and after treatment with poly (I:C) for 48h (induced). Tumor-infiltrating microglia/macrophages were isolated from ...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-25289 | biostudies-arrayexpress
ProteomicsFungal extract screening reveals malformin C to preferentially kill glioblastoma cells via concerted induction of proteotoxic stress and autophagic flux blockade
Azide-labelled malformin C or DMSO was incubated with protein lysate from patient derived glioblastoma stem-like cells (NCH421k), and a pulldown of the compound with Dibenzocyclooctyne (DBCO) agarose was performed in order to identify interacting proteins.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD046258 | Pride
Target deconvolution Glioblastoma Stem cells 
UnknownMicroglia isolated from patients with glioma gain antitumor activities on poly (I:C) stimulation.
Not available
S-EPMC3245995 | biostudies-literature
MetabolomicsTGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis

The mechanisms by which macrophage metabolism is regulated and the effects of metabolism on diseases remain largely unknown. We show here that TGF-β regulates the glycolysis of macrophages independently of inflammatory cytokine production, and thus affects the survival in experimental sepsis. Spe...

2023-02-17 | MTBLS6886 | MetaboLights
TranscriptomicsLOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients
MGMT promoter methylation status is currently the only established molecular prognosticator in IDH wild-type glioblastoma multiforme (GBM). Therefore, we aimed to discover novel therapy-associated epigenetic biomarkers. After enrichment for hypermethylated fractions using methyl-CpG-immunoprecipitat...
ORGANISM(S): Homo sapiens 
2016-03-10 | E-GEOD-74561 | biostudies-arrayexpress
UnknownMalformin C preferentially kills glioblastoma stem-like cells via concerted induction of proteotoxic stress and autophagic flux blockade.
Not available
S-EPMC11887673 | biostudies-literature
UnknownHuman Leucocyte Antigens as Prognostic Markers in Head and Neck Squamous Cell Carcinoma.
Not available
S-EPMC9367389 | biostudies-literature
UnknownMR Intensity Normalization Methods Impact Sequence Specific Radiomics Prognostic Model Performance in Primary and Recurrent High-Grade Glioma.
Not available
S-EPMC9913466 | biostudies-literature
UnknownWhen Immune Cells Turn Bad-Tumor-Associated Microglia/Macrophages in Glioma.
Not available
S-EPMC5855658 | biostudies-literature
UnknownGenome-Wide Expression Profiling of human tumor-infiltrating microglia/macrophages
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-25289 | biostudies-other
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