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UnknownCisplatin Eligibility Issues and Alternative Regimens in Locoregionally Advanced Head and Neck Cancer: Recommendations for Clinical Practice.
Not available
S-EPMC6579895 | biostudies-literature
TranscriptomicsMiRNA expression in adipose tissue and liver from a spontaneous rat model of Type 2 diabetes
MicroRNAs (miRNAs) are non-coding RNA molecules involved in post-transcriptional control of gene expression of a wide number of genes, including those involved in glucose homeostasis. Type 2 diabetes (T2D) is characterized by hyperglycaemia and defects in insulin secretion and action at target tissu...
ORGANISM(S): Rattus norvegicus 
2010-05-16 | E-GEOD-17058 | biostudies-arrayexpress
MetabolomicsUntargeted LC-MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase

INTRODUCTION: Interesting data about the family Asteraceae as a new source of Leishmania major dihydroorotate dehydrogenase (LmDHODH) inhibitors are presented. This key macromolecular target for parasites causing neglected diseases catalyzes the fourth reaction of the de novo pyr...

2019-10-14 | MTBLS722 | MetaboLights
TranscriptomicsFunctional heterogeneity of cancer-associated fibroblasts from human colon tumors shows specific prognostic gene expression signature
Tumor growth and metastasis is controlled by paracrine signaling between cells of the tumor microenvironment and malignant cells. Cancer-associated fibroblasts (CAFs), are functionally important components of the tumor microenvironment. Although some steps involved in the cross-talk between these ce...
ORGANISM(S): Homo sapiens 
2013-10-30 | E-GEOD-51257 | biostudies-arrayexpress
ProteomicsMolecular characterization of triple negative breast cancer formaldehyde-fixed paraffin-embedded samples by DIA proteomics
Triple negative breast cancer (TNBC) accounts for 15-20% of all breast carcinomas and it is clinically characterized by an aggressive phenotype and bad prognosis. TNBC does not benefit from any targeted therapy, so further characterization is needed to define subgroups with potential therapeutic val...
ORGANISM(S): Homo sapiens (Human) 
2022-02-14 | PXD021491 | Pride
Dia Ffpe Breast cancer Dia+ 
ProteomicsiTRAQ-based proteomic profile analysis of the hepatopancreas of Caribbean spiny lobsters infected with Panulirus argus virus 1: metabolic and physiological implications
The Caribbean spiny lobster Panulirus argus (Latreille, 1084) sustains economically valuable fisheries throughout the wider Caribbean region. This species is currently affected by the pathogenic virus Panulirus argus Virus 1 (PaV1). To date, there is no available information regarding the host alter...
ORGANISM(S): Panulirus Argus 
2020-04-29 | PXD018882 |
TranscriptomicsGenetic characterization of tumor-stage mycosis fungoides
Mycosis fungoides patients who develop tumors or extracutaneous involvement usually have a poor prognosis with no curative therapy available so far. In the present EORTC multicenter study, the genomic profile of 41 skin biopsies from tumor-stage mycosis fungoides was analyzed using a high-resolution...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-18098 | biostudies-arrayexpress
UnknownEfficacy of amoxicillin/clavulanic acid after surgical drainage of perianal abscess in the prevention of the development of anal fistula (PERIQxA study): study protocol for a multicenter randomized, double-blind clinical trial.
Not available
S-EPMC10868096 | biostudies-literature
UnknownEverolimus safety and efficacy for renal angiomyolipomas associated with tuberous sclerosis complex: a Spanish expanded access trial.
Not available
S-EPMC5037621 | biostudies-literature
UnknownCOVID-19 Severity and Survival over Time in Patients with Hematologic Malignancies: A Population-Based Registry Study.
Not available
S-EPMC10001264 | biostudies-literature
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