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ProteomicsBreast cancer cell lines in co-culture with hESC-derived nerual progenitor cells
In this study breast cancer cell lines were co-cultured with hESC-derived neural progenitor cells. Our aim was to determine how the breast cancer cellular proteomes were changed after one week in co-culture.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD040662 | Pride
Tmt 16-plex Breast cancer Cell lines Hesc-derived neural progenitor cells Co-culture Orbitrap fusion eclipse 
ProteomicsBreast cancer cell lines in co-culture with hESC-derived nerual progenitor cells
In this study breast cancer cell lines were co-cultured with hESC-derived neural progenitor cells. Our aim was to determine how the breast cancer cellular proteomes were changed after one week in co-culture.
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044553 | Pride
Neural progentior cell Human Cell culture Breast cancer 
TranscriptomicsGene expression analysis of H9 hESC derived cardiomyocytes (CM) and neuron stem cells (NSC)
In this study, we generated wildtype H9 hESC derived cardiomyocytes (CM) and neural stem cells (NSC) by in vitro differentiation. Global gene expression profiles were compared among undifferentiated H9 hESC and the derived CM and NSC. Comparison of global gene expression profiles of undifferentiated...
ORGANISM(S): Homo sapiens 
2013-08-31 | E-GEOD-48257 | biostudies-arrayexpress
TranscriptomicsIsolation and transcriptional profiling of embryonic human neural crest cells
To identify new candidate genes for neurocristopathies, a Long-SAGE library has been made from human neural crest cells (hNCC) derived from a normal embryo at Carnegie stage 13. Data analysis indicates the expression of a number of genes in multiple GO functional classes that were anticipated based...
ORGANISM(S): Homo sapiens 
2008-08-07 | E-GEOD-8368 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ESC line derived neural progenitor cells (hNPCs)
The self-renewal and differentiation potential of human embryonic stem cells (hESCs) suggests that hESCs could be used for regenerative medicine, especially for restoring neuronal functions in brain diseases. However, the functional properties of neurons derived from hESC are largely unknown. Moreov...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8347 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of gene expression patterns responding to TSA treatment during hESC neural differentiation
We report the differential roles of an HDAC inhibitor-TSA during hESC nerual commitment. In the initiation of hESC differentiation, TSA could inhibit the downregulation of pluripotency genes to maintain pluripotency, whereas in the neural commitment stage, TSA could promote neural gene expression to...
ORGANISM(S): Homo sapiens 
2015-03-11 | E-GEOD-66777 | biostudies-arrayexpress
TranscriptomicsTranscriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment
Human brain development is a complex process involving neural proliferation, differentiation, and migration which are directed by many essential cellular factors and drivers. Here, using the NetBID2 algorithm and developing human brain RNA sequencing(RNA-Seq) dataset, we identified synaptotagmin-lik...
ORGANISM(S): Homo sapiens 
2021-02-07 | E-MTAB-10058 | biostudies-arrayexpress
TranscriptomicsTransduction of human fibroblasts with Zic3 combined with OCT4, SOX2 and KLF4 induces stable neural progenitor cell lines
Lineage specific transcription factors (TF) define and reinforce tissue specific cell types. For instance, stable endoderm progenitors were established from human ESC by constitutive expression of SOX7 or SOX17. We hypothesized that combinatorial expression of OCT4, SOX2 and KLF4M-BM- together with ...
ORGANISM(S): Homo sapiens 
2012-05-21 | E-GEOD-29770 | biostudies-arrayexpress
TranscriptomicsComparsion of different hESC line derived neural progenitor cells (hNPCs)
The self-renewal and differentiation potential of human embryonic stem cells (hESCs) suggests that hESCs could be used for regenerative medicine, especially for restoring neuronal functions in brain diseases. However, the functional properties of neurons derived from hESC are largely unknown. Moreov...
ORGANISM(S): Homo sapiens 
2007-07-04 | GSE8347 | GEO
ProteomicsProteome profiling of an isogenic CAG allelic panel of Huntington disease hESCs and NPCs
Whole proteome profiling and quantification was performed on an isogenic Huntington disease (IsoHD) human embryonic stem cell (hESC) allelic panel. The IsoHD hESCs harbour 30, 45, 65 and 81 CAG repeats in the first exon of HTT. Whole proteome quantification was also performed on neural progenitor ce...
ORGANISM(S): Homo Sapiens (human) 
2019-02-14 | PXD006585 | JPOST Repository
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