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TranscriptomicsTranscription profiling of Streptomyces coelicolor strain M667 as a control for thiostrepton treatment
As a control for the effect of thiostrepton on gene expression in Streptomyces coelicolor, cultures of strain M667 [DrelA tipAp::] that lacks the truncated relA gene downstream of the thiostrepton-inducible promoter were treated with thiostrepton. Samples were harvested at 30 min intervals following...
ORGANISM(S): Streptomyces coelicolor 
2007-08-01 | E-MEXP-1120 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Streptomyces coelicolor strain M653 in a time series after ppGpp synthesis activation by thiostrepton
ppGpp synthesis was activated in exponentially growing cells of Streptomyces coelicolor in the absence of amino acid starvation by using a strain (M653 [DrelA tipAp::relA(1.46kb)]) that expresses a truncated portion of relA under the control of a thiostrepton-inducible promoter. Samples were harvest...
ORGANISM(S): Streptomyces coelicolor 
2007-08-01 | E-MEXP-1119 | biostudies-arrayexpress
TranscriptomicsResponse of Streptomyces coelicolor to treatment with the antibiotics vancomycin bacitracin and moenomycin A
To determine the response at the transcriptional level of S. coelicolor cells to treatment with 3 antibiotics that target distinct stages of cell wall biosynthesis, biological triplicate cultures of strain M600 were treated with sub-lethal concentrations (10 µg/ml) of vancomycin, bacitracin or moeno...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2011-04-29 | E-MEXP-3032 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Streptomyces coelicolor M570 ppGpp-deficient mutant and the parental strain M600
Comparison of the Streptomyces coelicolor relA mutant strain M570 with the parental strain M600 during growth on MYM agar.
ORGANISM(S): Streptomyces coelicolor 
2007-08-01 | E-MEXP-1098 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of yeast desiccation stress response to dessication in a time series
Response of Saccharomyces cerevisiae strain BY4741 to desiccation
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-16 | E-MEXP-2818 | biostudies-arrayexpress
TranscriptomicsRNA-seq of coding RNA of Pichia pastoris GS115 to determine the effect of inducing heterologous expression of human lysozyme (HuLy) variants
To determine the effect of inducing heterologous expression of human lysozyme (HuLy) variants in Pichia pastoris
ORGANISM(S): Pichia pastoris 
2013-09-12 | E-MTAB-1126 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of the effect of ppGpp, cdiAMP, and cdiGMP on Saccharomyces cerevisiae
Apart from the induction of host immune responses, any influence mediated by the presence of bacterial signalling molecules inside host cells on the latter’s physiology remains poorly defined. To determine the effects of the presence of ppGpp, cdiAMP and cdiGMP in the cytosol on the functioning of...
ORGANISM(S): Saccharomyces cerevisiae 
2017-07-26 | E-MTAB-5128 | biostudies-arrayexpress
TranscriptomicsRNA seq of Saccharomyces cerevisiae expressing pathways designed to increase ATP or GTP consumption
Many studies in yeast have observed correlations between changes in phosphorylated adenosine and guanosine nucleotide concentrations, and changes in cell physiology or gene expression. Evidence for a causal relationship is however sparse. To investigate this further under controlled conditions, we h...
ORGANISM(S): Saccharomyces cerevisiae 
2018-08-23 | E-MTAB-5174 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of Pichia pastoris GS115 to determine the effect of inducing heterologous expression of human lysozyme (HuLy) variants
To determine the effect of inducing heterologous expression of human lysozyme (HuLy) variants
ORGANISM(S): Pichia pastoris 
2017-09-17 | E-MTAB-562 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Streptomyces coelicolor M600 bldA deletion mutant vs. wild-type M600 S.coelicolor A3(2) time series
Time-dependent gene expression patterns during development and antibiotic production on solid growth medium (SMM) comparing a M600 bldA deletion mutant with wild-type M600 of S.coelicolor A3(2). Eight time points matched in all three replicates of both wild-type and mutant were picked to span the en...
ORGANISM(S): Streptomyces coelicolor 
2008-06-05 | E-MAXD-27 | biostudies-arrayexpress
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