Sort   by:  
 Page size 
ProteomicsProtein disulfide isomerase ERp57 protects early muscle denervation in experimental ALS
Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice overexpressing ALS-linked mutant SOD1 develop ALS symptoms accompanied by histopat...
ORGANISM(S): Mus musculus (Mouse) 
2021-02-08 | PXD023647 | Pride
Neuromuscular junction Erp57 Protein aggregation Amyotrophic lateral sclerosis Mutant sod1 
TranscriptomicsTranscriptional responses in liver upon acute CCl4 intoxication
Since xenobiotics enter the organism via the liver, hepatocytes must cope with numerous perturbations. In particular, exposure to hepatotoxic agents resulting in liver injury triggers a strong alteration in gene expression. The contribution of these transcriptional regulatory networks to the propaga...
ORGANISM(S): Mus musculus 
2014-08-31 | E-MTAB-2445 | biostudies-arrayexpress
TranscriptomicsDual IRE1 RNase functions dictate glioblastoma development
The transcriptome dataset has been used to validate on a GBM patient cohort (n=117) the IRE1-dependent gene expression signature identified in U87 cell line.
ORGANISM(S): Homo sapiens 
2018-01-09 | E-MTAB-6326 | biostudies-arrayexpress
UnknownUnfolded protein response IRE1/XBP1 signaling is required for healthy mammalian brain aging
Not available
S-SCDT-EMBOJ-2022-111952 | biostudies-other
Sort   by:  
 Page size