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TranscriptomicsNRG1/ERBB3 signaling in melanocyte Melan-Ink4a cells
Neuregulin (NRG) signaling through the receptor tyrosine kinase, ERBB3, is required for embryonic development, and dysregulated signaling has been associated with cancer progression. Here, we show that NRG1/ERBB3 signaling inhibits melanocyte (MC) maturation and promotes undifferentiated, migratory ...
ORGANISM(S): Mus musculus 
2010-05-07 | E-GEOD-21463 | biostudies-arrayexpress
TranscriptomicsGenomic diversity of a pneumococcal clonal complex, 199
Comparative genomic hybridisation of Streptococcus pneumoniae isolates from a single clonal complex, in order to determine genomic diversity. Isolates were selected from a range of tissue types and serotypes in order to cover the full diversity of the clone, and also in order to try and identify tis...
ORGANISM(S): Streptococcus pneumoniae 
2010-09-07 | E-GEOD-23992 | biostudies-arrayexpress
TranscriptomicsWhole genome transcritptional comparison of Group A Streptococcus (Streptococcus pyogenes) serotype M1 pre-epidemic and epidemic isolates
This transcriptional analysis is a follow up to a population genomic investigation of 3615 Streptococcus pyogenes serotype M1 strains whch are responsible for an epidemic of human invasive infections (www.pnas.org/cgi/doi/10.1073/pnas.1403138111), The goal was to assess gene expression differences b...
ORGANISM(S): Streptococcus pyogenes 
2015-08-10 | E-GEOD-70496 | biostudies-arrayexpress
UnknownA randomised controlled trial to assess the clinical effectiveness and safety of the endometrial scratch procedure prior to first-time IVF, with or without ICSI.
Not available
S-EPMC8213451 | biostudies-literature
UnknownCopy number variations of TBK1 in Australian patients with primary open-angle glaucoma.
Not available
S-EPMC4355400 | biostudies-literature
ProteomicsA dataset describing a suite of novel antibody reagents for the RAS signaling network
RAS genes are frequently mutated in cancer and have for decades eluded effective therapeutic attack. The National Cancer Institute’s RAS Initiative has a focus on understanding pathways and discovering therapies for RAS-driven cancers. Part of these efforts is the generation of novel reagents to ena...
ORGANISM(S): Homo Sapiens 
PXD012604 | panorama
ProteomicsTargeted mass spectrometry enables multiplexed quantification of immunomodulatory proteins in clinical biospecimens
Immunotherapies are revolutionizing cancer care, producing durable responses and potentially cures in a subset of patients. However, response rates are low for most tumors, grade 3/4 toxicities are not uncommon, and our current understanding of tumor immunobiology is incomplete. While hundreds of im...
ORGANISM(S): Homo Sapiens 
2022-02-28 | PXD029167 | panorama
UnknownHip fracture evaluation with alternatives of total hip arthroplasty versus hemiarthroplasty (HEALTH): protocol for a multicentre randomised trial.
Not available
S-EPMC4330331 | biostudies-literature
UnknownA common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.
Not available
S-EPMC4605818 | biostudies-literature
UnknownTotal medical costs of treating femoral neck fracture patients with hemi- or total hip arthroplasty: a cost analysis of a multicenter prospective study.
Not available
S-EPMC4869739 | biostudies-literature
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