Sort   by:  
 Page size 
MetabolomicsTargeted metabolomic analysis on hexosamine biosynthetic pathway in flies on time restricted feeding
Not available
ORGANISM(S): Drosophila melanogaster 
ST001452 | MetabolomicsWorkbench
MetabolomicsM3-Driven Hexosamine Biosynthesis Facilitates Hepatocellular Carcinoma Progression through YBX1 O-GlcNAcylation
Phosphoglucomutase 3 (PGM3) is one of the rate-limiting enzymes in the hexosamine biosynthesis pathway (HBP) and a key regulator of HBP metabolic flux. Despite the functional role of PGM3 has been validated in various tumors, its function and molecular mechanism in hepatocellular carcinoma (HCC) rem...
2026-09-04 | MTBLS15552 | MetaboLights
MetabolomicsPGM3-Driven Hexosamine Biosynthesis Facilitates Hepatocellular Carcinoma Progression through YBX1 O-GlcNAcylation (Untargeted metabolomics)
Phosphoglucomutase 3 (PGM3) is one of the rate-limiting enzymes in the hexosamine biosynthesis pathway (HBP) and a key regulator of HBP metabolic flux. Despite the functional role of PGM3 has been validated in various tumors, its function and molecular mechanism in hepatocellular carcinoma (HCC) rem...
2026-09-03 | MTBLS15545 | MetaboLights
TranscriptomicsTranscription profiling by array of human DA-MB-231 breast cancer cells treated with various SCFA-hexosamine analogs
The purpose of this study was to characterize the gene expression profile of MDA-MB-231 breast cancer cells treated with various SCFA-hexosamine analogs to better understand the role of various modifications to this scaffold. Experiment Overall Design: In total, six analogs were investigated in this...
ORGANISM(S): Homo sapiens 
2009-05-17 | E-GEOD-11407 | biostudies-arrayexpress
ProteomicsThe role of RelA in RSV-mediated N-glycosylation
This study is to examine the role of RelA in regulation the activation of hexosamine biosynthetic pathway and N-glycosylation in RSV infection
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD034013 | Pride
Innate immunity Rsv Epigenetic regulation Hexosamine biosynthetic pathway 
TranscriptomicsKras is required for pancreatic tumor maintenance through regulation of hexosamine biosynthesis and the non-oxidative pentose phosphate pathway
The maintenance of advanced malignancies relies on continued activity of driver oncogenes, although their rate-limiting role is highly context-dependent with respect to tumor types and associated genetic alterations. Oncogenic Kras mutation is the signature event in human pancreatic ductal adenocar...
ORGANISM(S): Mus musculus 
2012-04-29 | E-GEOD-32277 | biostudies-arrayexpress
UnknownHyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway.
Not available
S-EPMC5533945 | biostudies-literature
TranscriptomicsPathway-based integrative analysis reveals a key role for the hexosamine biosynthetic pathway in castrate resistant prostate cancer with therapeutic implications
The development and progression of castrate resistant prostate cancer (CRPC), a lethal disease, is thought to be driven by multiple events. A hallmark of CRPC is the ability to evade the cytotoxic effects of anti-androgen therapy. Importantly, persistent androgen receptor (AR) signalling is thought ...
ORGANISM(S): Homo sapiens 
2015-04-03 | E-GEOD-67537 | biostudies-arrayexpress
UnknownIncreased hexosamine biosynthetic pathway flux alters cell-cell adhesion in INS-1E cells and murine islets.
Not available
S-EPMC10403402 | biostudies-literature
UnknownNutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway.
Not available
S-EPMC4891703 | biostudies-literature
Sort   by:  
 Page size