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MetabolomicsMetabolomic Analysis Reveals an Important Role of Sphingosine 1-phosphate in the Development of HFMD due to EV-A71 Infection

Hand, foot, and mouth disease (HFMD) is a serious pediatric infectious disease that causes immeasurable physical and mental health burdens. Currently, there is a lack of information on the mechanisms of HFMD severity and early diagnosis. We performed metabolomic profiling of sera from 84 Enterovi...

2024-11-14 | MTBLS11656 | MetaboLights
GenomicsTranscriptome analysis of brainstem in gerbils with CA16-infection-induced HFMD
Transcriptome analysis of brainstem in gerbils with CA16-infection-induced HFMD
PRJNA501869 | ENA
GenomicsTranscriptome analysis of brainstem in gerbils with EV71-infection-induced HFMD
Transcriptome analysis of brainstem in gerbils with EV71-infection-induced HFMD
PRJNA509196 | ENA
TranscriptomicsTranscriptome analysis of brainstem in gerbils with EV71-infection-induced HFMD
Enterovirus 71 (EV71) is one of the major pathogens associated with human hand, foot, and mouth disease (HFMD) and in some countries this pathogen is the leading cause of this disease. We previously found that CA16 could induce neurological disorders in young gerbils, which could serve as a good ani...
ORGANISM(S): Meriones unguiculatus 
2019-06-07 | GSE123550 | GEO
TranscriptomicsTranscriptome analysis of brainstem in gerbils with CA16-infection-induced HFMD
Coxsackievirus A16 (CA16) is one of the major pathogens associated with human hand, foot, and mouth disease (HFMD) and in some countries this pathogen is the leading cause of this disease. We previously found that CA16 could induce neurological disorders in young gerbils, which could serve as a good...
ORGANISM(S): Meriones unguiculatus 
2019-06-07 | GSE121971 | GEO
GenomicsFelis catus strain:Kinkalow
Whole genome sequencing for Hypertrophic feline muscular dystrophy (HFMD)
PRJDB16308 | ENA
UnknownAssociation of environmental factors and high HFMD occurrence in northern Thailand.
Not available
S-EPMC7706220 | biostudies-literature
UnknownImpaired arginine/ornithine metabolism drives severe HFMD by promoting cytokine storm.
Not available
S-EPMC11228176 | biostudies-literature
TranscriptomicsTranscriptomic Analysis Initially Reveals Monocyte/Macrophage Activation Drives EV-A71-Induced Immune Dysregulation and Neural Injury in Severe HFMD
Objective Enterovirus 71 (EV-A71) is a major pathogen of severe hand, foot and mouth disease (HFMD) in children, but the mechanism by which it develops into severe HFMD remains unclear, especially the role of macrophage-mediated immune dysregulation. Methods Macrophages infected with EV-A71 were col...
ORGANISM(S): Enterovirus A71 
2025-09-10 | GSE304239 | GEO
UnknownDaily mean temperature and HFMD: risk assessment and attributable fraction identification in Ningbo China.
Not available
S-EPMC8263339 | biostudies-literature
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