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After DNA damage, cells activate p53, a tumor suppressor gene, and select a cell fate (e.g., DNA repair, cell cycle arrest, or apoptosis). Recently, a p53 oscillatory behavior was observed following DNA damage. However, the relationship between this p53 oscillation and cell-fate selection is unclear...
2024-09-02 | BIOMD0000000939 | BioModels
Cell lysates were prepared from Tmem63b-GFP-expressing BDKO cells and incubated with the GFP-Trap magnetic agarose beads (Proteintech). After rotation at 4˚C for 3 hr, the beads were precipitated with the magnet, followed by washing several times using wash buffer containing 25 mM Tris-HCl (pH 8.0),...
ORGANISM(S): Mus Musculus (mouse) 
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