High grade glioma

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Unknown (2486)
Transcriptomics (795)
Genomics (466)
Proteomics (64)
Methylation profiling (22)
Metabolomics (14)
Other (8)
Clinical (4)

Organisms

Homo sapiens (771)
Mus musculus (185)
Saccharomyces cerevisiae (36)
Rattus norvegicus (36)
Homo sapiens (36)
Shigella flexneri (36)
Rattus norvegicus (26)
Danio rerio (13)
Daphnia magna (9)
synthetic construct (4)
Schizosaccharomyces pombe (3)
Lemna minor (2)
Pimephales promelas (2)
Zea mays (2)
Nitrosomonas europaea (1)
Micropterus salmoides (1)
uncultured bacterium (1)
Papio anubis (1)
Ambystoma mexicanum (1)
Schizosaccharomyces pombe 972h- (1)
Selaginella moellendorffii (1)
Chlorocebus sabaeus (1)
Listeria monocytogenes (1)
Rattus rattus (1)
Oncorhynchus mykiss (1)
Bos taurus (1)
Caenorhabditis elegans (1)
Gallus gallus (1)
Arabidopsis thaliana (1)
Canis lupus familiaris (1)

Organisms

Homo sapiens (174)
Mus musculus (72)
Schizosaccharomyces pombe (3)
Canis lupus familiaris (1)

Repository

biostudies-arrayexpress (674)
ENA (289)
geo (221)
EGA (116)
pride (36)
MetaboLights (14)
MassIVE (12)
jPOST (5)
PanoramaPublic (4)
iProX (3)
ExpressionAtlas (1)
PeptideAtlas (1)

Tissue

Brain (24)
Cell culture (11)
Stem cell (3)
Macroglial cell (2)
Astrocyte (2)
Glial cell (2)
Brain (1)
Glioma cell (1)
Neutrophil (1)
Melanocyte (1)
Malignant cell (1)
Permanent cell line cell (1)
Blood plasma (1)
Epithelial cell (1)

Disease

Glioblastoma (19)
Normal (10)
Central nervous system cancer (6)
Glioma (3)
Glioblastoma multiforme (3)
Glioma (3)
Pilocytic astrocytoma (2)
High grade glioblastoma (2)
Oligodendroglioma (2)
Adult high grade glioma (1)
Atypical teratoid/rhabdoid tumor (1)
Group 3 medulloblastoma (1)
Group 4 medulloblastoma (1)
Pediatric high grade glioma (1)
Posterior fossa group A ependymoma (1)
Posterior fossa group B ependymoma (1)
Sonic hedgehog group medulloblastoma (1)
Supratentorial ependymoma (1)
Astrocytoma (1)
Astrocytomas (1)
Non-classic glioblastoma (1)
Dermal neurofibroma (1)
Ependymoma (1)
Liposarcoma (1)
Oligodendroglioma (1)
Giant cell glioblastoma (1)
Cancer cell line pool (1)
Giant Cell Glioblastoma (1)
Temporal lobe epilepsy (1)
Astrocytoma III (1)

Technology Type

Mass Spectrometry (36)
Shotgun proteomics (21)
Mass spectrometry (12)
Top-down proteomics (5)
Illumina HiSeq 2000 (4)
Affinity purification coupled with mass spectrometry proteomics (4)
ILLUMINA, Illumina HiSeq 2000 (3)
Bottom-up proteomics (3)
SRM/MRM (2)
Data-dependent acquisition (2)
Illumina HiSeq 4000, Illumina HiSeq 2500, ILLUMINA (1)
Affymetrix_U133v2, Illumina HiSeq 2000 (1)
Illumina HiSeq 2500, Illumina HiSeq 2000 (1)
ILLUMINA, Illumina HiSeq 2000 (ILLUMINA), Illumina HiSeq 2000 (1)
NMR spectroscopy (1)
Mass spectrometry assay (1)
Affinity proteomics (1)
Mass spectrometry imaging (1)
Gel-based experiment (1)
HDMSE (1)
SWATH MS (1)

Instrument Platform

Illumina HiSeq 4000 (15)
NextSeq 500 (15)
Illumina NovaSeq 6000 (12)
Illumina HiSeq 2500 (5)
Illumina iScan (4)
IScan (3)
Ion Torrent Proton (3)
Illumina HiSeq 2000 (3)
Illumina Hybridisation Oven (2)
ScanArray 5000 [PerkinElmer] (2)
DNA Microarray Scanner BA [Agilent Technologies] (2)
Q Exactive HF (2)
LTQ Orbitrap (2)
Illumins Hybridisation Oven (1)
Raven (Wales High-performance computing cluster) (1)
DNA 7500 Bioanalyzer Chips (1)
MoFlo Legacy cell sorter (Beckman Coulter) (1)
PC (1)
GenePix Personal 4100A [Axon Instruments] (1)
G2565AA DNA microarray scanner [Agilent] (1)
Illumina Genome Analyzer IIx (1)
418 [Affymetrix] (1)
ScanArray 4000XL [PerkinElmer] (1)
FACS Aria (1)
Illumina MiSeq (1)
Illumina HiSeq 1500 (1)
AB 5500xl Genetic Analyzer (1)
Q-Exactive Orbitrap HF (1)
LTQ (1)
Exactive Plus (1)

Publication Date

2013 (112)
2012 (83)
2015 (77)
2014 (74)
2010 (71)
2011 (67)
2025 (53)
2016 (51)
2024 (50)
2021 (50)
2026 (44)
2023 (38)
2022 (33)
2008 (29)
2020 (25)
2009 (23)
2019 (22)
2018 (22)
2007 (18)
2017 (17)
2006 (7)
2005 (4)

UNIPROT ID/AC

Q7Z3Z4 (1)
Q5VZB9 (1)
P19526 (1)
Q9NT99 (1)
Q9Y342 (1)
Q9UH77 (1)
Q02246 (1)
P57087 (1)
Q6UWR7 (1)
Q6PJP8 (1)
O15516 (1)
P26012 (1)
P04271 (1)
P26022 (1)
Q96J42 (1)
Q8TBC5 (1)
Q9H313-3 (1)
Q16620 (1)
P42658-2 (1)
P42658 (1)
P23515 (1)
P36222 (1)
P28702 (1)
O43157 (1)
Q7Z3B1 (1)
Q16790 (1)
P50150 (1)
Q9P121 (1)
Q9H313 (1)
Q9BY11 (1)

ENSEMBL ID

ENSG00000229353 (1)
ENSG00000170477 (1)

CHEBI ID

CHEBI:16811 (5)
CHEBI:16668 (5)
CHEBI:15891 (5)
CHEBI:17509 (4)
CHEBI:16750 (4)
CHEBI:16704 (4)
CHEBI:15356 (4)
CHEBI:17822 (4)
CHEBI:28044 (4)
CHEBI:16708 (4)
CHEBI:16737 (4)
CHEBI:16919 (4)
CHEBI:17596 (4)
CHEBI:16856 (4)
CHEBI:28300 (4)
CHEBI:18237 (4)
CHEBI:30769 (4)
CHEBI:16027 (4)
CHEBI:16335 (4)
CHEBI:21557 (3)
CHEBI:18186 (3)
CHEBI:16870 (3)
CHEBI:15414 (3)
CHEBI:16450 (3)
CHEBI:17202 (3)
CHEBI:17713 (3)
CHEBI:48928 (3)
CHEBI:15698 (3)
CHEBI:27823 (3)
CHEBI:18132 (3)

Metabolite Name

Methionine (4)
Inosine (4)
Hypotaurine (3)
Cysteine (3)
Serine (3)
Taurine (3)
Pyridoxine (3)
Hypoxanthine (3)
Adenine (3)
Creatinine (3)
Glutathione (3)
Leucine (3)
Glutamine (3)
Glutamate (3)
ADP (3)
Adenosine (3)
Guanosine (3)
Uridine (3)
Cytosine (3)
Keracyanin (2)
Indole-3-acetaldehyde (2)
O-Phosphoethanolamine (2)
N-formylmethionine (2)
5-hydroxyindoleacetate (2)
3-hydroxykynurenine (2)
Indole-3-carboxylic acid (2)
Sn-Glycero-3-phosphocholine (2)
2'-deoxycytidine (2)
1-methylhistidine (2)
Allocryptopine (2)

First Public Date

2025 (51)
2026 (45)
2024 (42)
2021 (29)
2023 (28)
2014 (22)
2020 (21)
2019 (13)
2022 (10)
2018 (9)
2015 (8)
2017 (7)
2016 (2)
2013 (2)

Modification

4-dinitrophenyl modified residue (1)
Not available (1)

Study status

Completed (2)
Terminated (1)
Recruiting (1)

Study type

Transcription profiling by array (413)
RNA-seq of coding RNA (66)
Comparative genomic hybridization by array (46)
Methylation profiling by array (35)
ChIP-seq (23)
Genotyping by array (17)
Other (8)
Unknown experiment type (7)
ChIP-chip by tiling array (6)
Transcription profiling by RT-PCR (6)
Animal - High-throughput sequencing (5)
Cell line - High-throughput sequencing (4)
MicroRNA profiling by array (4)
Interventional (4)
Proteomic profiling by array (3)
RNA-seq of coding RNA from single cells (3)
Methylation profiling by high throughput sequencing (3)
RNA-seq of total RNA (3)
Cell line - Methylation microarray (2)
MicroRNA profiling by high-throughput sequencing (2)
Human - High-throughput sequencing (2)
DNA-seq (2)
Transcription profiling by MPSS (1)
One-color microarray (1)
Cell line - One-color microarray (1)
RNAi profiling by array (1)
ChIP-chip by array (1)
Ribo-seq (1)
RNA-seq of non coding RNA (1)

Release Date

2022 (372)
2021 (342)
2023 (284)
2024 (249)
2025 (240)
2020 (220)
2016 (162)
2019 (154)
2015 (152)
2013 (150)
2014 (147)
2018 (139)
2017 (135)
2012 (111)
2011 (92)
2010 (80)
2008 (37)
2009 (31)
2026 (30)
2007 (18)
2006 (6)
2005 (6)
2003 (2)
2002 (1)

Lab affiliation

UHN (3)
changzhi medical college (2)
Institute of Bioinformatics, Bangalore - 560066, India (2)
Brainstorm Brain Cancer Research, Brain and Mind Centre, University of Sydney, NSW, Australia School of Life and Environmental Science, University of Sydney, New South Wales, Australia (1)
Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, China (1)
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany German Cancer Research Center (DKFZ), Clinical Cooperation Unit Pediatric Oncology , Heidelberg, Germany (1)
The Shraga Segal Department of Microbiology, Immunology and Genetics,National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, P.O.B. 653, Be'er-Sheva 84105, Israel (1)
Chemistry Institute, LADETEC, Proteomics Laboratory, UFRJ, RJ, Brazil. (1)
Institute of Biochemistry II, Goethe University Hospital Frankfurt/Main, Germany (1)
Biosciences and Bioengineering, IIT Bombay, India (1)
Laboratoire PRISM INSERM U1192 Université de Lille Villeneuve d'ascq France (1)
Molecular Proteomics Laboratory Biological-Medical Research Center Heinrich Heine University Düsseldorf Universitätsstraße 1 40225 Düsseldorf Germany (1)
Protemics Service CIC bioGUNE Bizkaia Tech. Park Build. 800 48160 Derio (Spain) (1)
Goethe University Frankfurt, Institute of molecular systems medicine (1)
Koç University, Turkey (1)
Department of Oncology and Children's Research Center, University Children's Hospital of Zurich, Zurich, Switzerland (1)
Center of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn University (1)
Institute of Biochemistry II, Goethe University Frankfurt, Germany (1)
Protein Analysis Core Facility German Cancer Research Center (DKFZ) (1)
Laboratory for structural and computational proteomics - Carlos Chagas Institute, Fiocruz Paraná, Brazil (1)
Head of Laboratory of Neuro-Oncology, Neurology, Clinical & Cancer Proteomics (1)
Center for Cell and Gene Therapy Department of Neurosurgery Baylor College of Medicine Houston, Texas, USA (1)
Proteomics Service CIC bioGUNE Bizkaia Tech. Park Build. 800 Derio 48160 Spain (1)
Proteomics facility, Central Science Laboratory, University of Tasmania (1)
PRISM - Unité Inserm 1192 Université de Lille France (1)
Department of Neurology, Clinical Neuroscience Center, University Hospital and University of Zurich; Zurich, Switzerland (1)
Yale University (1)
Epigenetics and Cell Fate Centre CNRS UMR7216 – Université Paris Cité Lamarck B building, 4th floor, room 413 35, rue Hélène Brion 75205 Paris Cedex 13 +33157278981 (1)
Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany NNF Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark (1)
St. Jude Children's Research Hospital (1)

Location

Canada (3)
United States (3)
Norway (1)
North Korea (1)
Asia except Japan (1)
Denmark (1)
Europe (1)
North America (1)
Sweden (1)
Germany (1)
Netherlands (1)
Austria (1)
Japan (1)
Spain (1)
Italy (1)
France (1)
Belgium (1)
South Korea (1)

Keyword

Thallion (1)
TLN-4601 (1)
Ecopia (1)
ECO-4601 (1)
Patients with histologically confirmed solid tumors: (1)
High Grade Glioma (1)
Tafinlar (1)
Anaplastic thyroid cancer (ATC) (1)
Biliary tract cancer (BTC) (1)
Low grade (WHO G1/G2) glioma (LGG) (1)
High grade (WHO G3/G4) glioma (HGG) (1)
Non-seminomatous germ cell tumors (NSGCT)/non-germinomatous germ cell tumors (NGGCT) (1)
Adenocarcinoma of the small intestine (ASI) (1)
Hairy cell leukemia (HCL) (1)
Gastrointestinal stromal tumor (GIST) (1)
BRAF V600E mutation (1)
Breast (1)
Flucytosine (1)
Anaplastic Astrocytoma, Glioblastoma (1)
Multiple myeloma (MM) (1)
Safety (1)
Dabrafenib (1)
Efficacy (1)
Lung (1)
Pancreatic (1)
Trametinib (1)
Prostate (1)
Pembrolizumab (1)
Colorectal (1)
Ovarian (1)

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Tissue metabolites in diffuse glioma and their modulations by IDH1 mutation, histology, and treatment

The discovery of the oncometabolite 2-hydroxyglutarate in isocitrate dehydrogenase 1-mutated (IDH1-mutated) tumor entities affirmed the role of metabolism in cancer. However, large databases with tissue metabolites that are modulated by IDH1 mutation remain an area of development. Here, we present a...

2022-09-07 | MTBLS3873 | MetaboLights

SNAP25 inhibits glioma progression by regulating synapse plasticity via GLS-mediated glutaminolysis

INTRODUCTION: Neuronal activity regulated by synaptic communication exerts an important role in tumorigenesis and progression in brain tumors. Genes for soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) annotated with the function ‘vesicle’ about syn...

2021-08-12 | MTBLS2806 | MetaboLights

Transcription profiling of 20 human primary high grade glioma cell cultures

Gene expression profiling of 20 primary high grade glioma cell cultures

ORGANISM(S): Homo sapiens

2007-05-31 | E-MEXP-1063 | biostudies-arrayexpress

Comprehensive Mapping of Paediatric High Grade Glioma

Overall paediatric high grade glioma (pHGG) has a poor prognosis, in part due to the lack of understanding of the underlying biology. We therefore used high resolution 244k oligo array comparative genomic hybridisation (oligo aCGH) (Agilent Technologies) to analyse DNA from 38 formalin-fixed paraf...

ORGANISM(S): Homo sapiens

2010-12-01 | E-GEOD-21420 | biostudies-arrayexpress

Transcription profiling of high and low grade gliomas from human patients to identify new diagnostic and prognostic markers

Comparison of high grade to low grade gliomas.

ORGANISM(S): Homo sapiens

2007-06-01 | E-TABM-167 | biostudies-arrayexpress

F11R is a novel monocyte prognostic biomarker for malignant glioma [Seq]

Objective: Brain tumors (gliomas) contain large populations of infiltrating macrophages and recruited microglia, which in experimental murine glioma models promote tumor formation and progression. Among the barriers to understanding the contributions of these stromal elements to high-grade glioma (g...

ORGANISM(S): Mus musculus

2013-11-13 | E-GEOD-46688 | biostudies-arrayexpress

Glioma miRNA expression profile

Comparison of the miRNAs profile of 8 WHO grade II gliomas and 24 higher grade tumors (2 WHO grade III and 22 glioblastomas) in order to identify the molecular determinants of progression.

ORGANISM(S): Homo sapiens

2014-03-15 | E-MTAB-1840 | biostudies-arrayexpress

Human glioma cells: chronophin (CIN/PDXP) knockdown vs. control or rescue

Transcriptional profiling of human glioma cells to elucidate the role of chronophin (CIN/PDXP) for glioma pathogenesis three-condition experiment: control cells vs. knockdown and knockdown vs. rescue

ORGANISM(S): Homo sapiens

2015-11-25 | E-GEOD-71786 | biostudies-arrayexpress

F11R is a novel monocyte prognostic biomarker for malignant glioma [Affymetrix]

ORGANISM(S): Mus musculus

2013-11-13 | E-GEOD-46686 | biostudies-arrayexpress

miRNA analysis of HBMVECs exposed or unexposed to U87 glioma cells

A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells. Here we demonstrate that a small regulatory microRNA, miR-296 has a major role in this process. Glioma cells and angiogenic growth factors elevate the level of miR-296 in primary human brain microvascular...

ORGANISM(S): Homo sapiens

2010-06-25 | E-GEOD-13091 | biostudies-arrayexpress

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