High mobility group proteins

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Unknown (518)
Proteomics (374)
Transcriptomics (166)
Genomics (71)
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Multiomics (2)

Organisms

Homo sapiens (78)
Mus musculus (78)
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Glycine max (1)
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Caenorhabditis elegans (1)
Gallus gallus (1)
Streptococcus pneumoniae D39 (1)

Organisms

Mus musculus (15)
Homo sapiens (6)
Plasmodium falciparum (4)
Saccharomyces cerevisiae (3)
Austrofundulus limnaeus (1)
Schizosaccharomyces pombe (1)
Drosophila melanogaster (1)
Entamoeba histolytica (1)
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Rattus norvegicus (1)

Repository

pride (305)
biostudies-arrayexpress (167)
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geo (35)
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Cell culture (82)
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Disease

COVID-19 (11)
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Disease free (4)
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Normal (1)
Acute leukemia (1)
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Amyotrophic lateral sclerosis (1)
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Asthma (1)
Azoospermia (1)
Bacterial infectious disease (1)

Technology Type

Mass Spectrometry (305)
Bottom-up proteomics (102)
Shotgun proteomics (96)
Data-independent acquisition (87)
Data-dependent acquisition (39)
HDMSE (31)
DiaPASEF (19)
SWATH MS (16)
Affinity purification coupled with mass spectrometry proteomics (14)
Top-down proteomics (8)
All-ion fragmentation (7)
MSE (7)
Mass spectrometry (6)
Gel-based experiment (5)
Affinity proteomics (4)
SRM/MRM (3)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
Illumina HiSeq 2000, ILLUMINA (1)
Mass spectrometry assay (1)
Immunopeptidomics (1)
Mass spectrometry imaging (1)
Metaproteomics (1)

Instrument Platform

Q Exactive (17)
Orbitrap Fusion (5)
Illumina NovaSeq 6000 (4)
Orbitrap Eclipse (4)
Orbitrap Fusion Lumos (4)
TSQ Quantiva (4)
TimsTOF Pro (4)
LTQ Orbitrap Elite (3)
LTQ Orbitrap Velos (3)
Orbitrap Exploris 480 (3)
Instrument (2)
LTQ Orbitrap (2)
MicrOTOF-Q II (2)
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GeneChip Hybridization Oven 645 (1)
GeneChip Scanner 3000 7G (1)
BAS-1800 [FUJIFILM] (1)
GenePix 4000A [Axon Instruments] (1)
G2565AA DNA microarray scanner [Agilent] (1)
418 [Affymetrix] (1)
GenePix 4000B [Axon Instruments] (1)
Illumina Genome Analyzer II (1)
Illumina MiSeq (1)
Illumina HiSeq 2500 (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 4000 (1)
6560 Q-TOF LC/MS (1)
SYNAPT G2-Si (1)
SolariX (1)
TimsTOF (1)

Publication Date

2025 (105)
2024 (72)
2026 (67)
2023 (36)
2022 (30)
2014 (26)
2020 (23)
2013 (22)
2017 (21)
2012 (20)
2011 (20)
2010 (19)
2021 (17)
2018 (15)
2015 (15)
2008 (15)
2016 (14)
2019 (12)
2007 (10)
2009 (8)
2006 (3)
2005 (1)
2004 (1)

UNIPROT ID/AC

3MG1_ECOLI (1)
3PASE_ECOLI (1)
5DNU_ECOLI (1)
6PGD_ECOLI (1)
6PGL_ECOLI (1)
A2MG_ECOLI (1)
AAAT_ECOLI (1)
AAER_ECOLI (1)
AAS_ECOLI (1)
AAT_ECOLI (1)
ACCA_ECOLI (1)
ACCC_ECOLI (1)
ACCD_ECOLI (1)
ACEA_ECOLI (1)
ACFD_ECOLI (1)
ACKA_ECOLI (1)
ACNA_ECOLI (1)
ACNB_ECOLI (1)
ACPH_ECOLI (1)
ACPS_ECOLI (1)
ACPT_ECOLI (1)
ACP_ECOLI (1)
ACRA_ECOLI (1)
ACRB_ECOLI (1)
ACSA_ECOLI (1)
ACUI_ECOLI (1)
ACYP_ECOLI (1)
ADD_ECOLI (1)
ADEC_ECOLI (1)
ADEP_ECOLI (1)

CHEBI ID

CHEBI:64575 (2)
CHEBI:17858 (2)
CHEBI:16695 (2)
CHEBI:16704 (2)
CHEBI:16027 (2)
CHEBI:89976 (1)
CHEBI:89756 (1)
CHEBI:88400 (1)
CHEBI:88472 (1)
CHEBI:229635 (1)
CHEBI:88350 (1)
CHEBI:186598 (1)
CHEBI:186597 (1)
CHEBI:165657 (1)
CHEBI:165646 (1)
CHEBI:186595 (1)
CHEBI:186593 (1)
CHEBI:186591 (1)
CHEBI:186587 (1)
CHEBI:60356 (1)
CHEBI:186585 (1)
CHEBI:186584 (1)
CHEBI:186582 (1)
CHEBI:186578 (1)
CHEBI:186576 (1)
CHEBI:186574 (1)
CHEBI:165656 (1)
CHEBI:186572 (1)
CHEBI:186571 (1)
CHEBI:187869 (1)

Metabolite Name

MAG 18:0 (2)
Uridine (2)
Creatine (2)
L-Valine (2)
PC O-16:0/20:4 (1)
PE 16:0/22:6 (1)
PC 20:4/20:4 (1)
PC 16:1/20:4 (1)
PE 18:1/20:4 (1)
PC 16:0/14:0 (1)
DAG 18:0/20:4 (1)
TAG 16:0/18:1/18:1 (1)
TAG 16:0/18:1/20:1 (1)
TAG 16:0/16:0/20:4 (1)
TAG 16:1/16:1/18:1 & TAG 16:0/14:0/20:3 (1)
TAG 18:1/18:1/20:1 (1)
TAG 16:1/16:1/18:2 (1)
TAG 16:0/18:1/20:4 (1)
TAG 16:0/18:1/18:2 (1)
4-(4-hydroxyphenyl)sulfonylphenol (1)
NAD⁺ (1)
Glu-glu (1)
Alpha-Pyrrolidinopentiophenone (1)
Porphyrinogen (1)
2-glyceryl-11,12-EET (1)
Stilbene (1)
Corchoionoside C (1)
N-Benzyl-9-(tetrahydro-2H-pyran-2-yl)adenine (1)
Nortrachelogenin (1)
DIGOXIN (1)

First Public Date

2014 (9)
2026 (7)
2023 (4)
2024 (3)
2017 (3)
2025 (2)
2019 (2)
2018 (2)
2013 (2)
2022 (1)
2021 (1)
2016 (1)
2015 (1)

Classification

protozoa (5)

Modification

+3amu) (1)
-17.026549 (1)
15.994915 (1)
32.056407 (1)
42.010565 (1)
45.029395 (1)
4x(2)H labeled dimethylated residue (1)
N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (110)
ChIP-seq (16)
RNA-seq of coding RNA (9)
Unknown experiment type (4)
ChIP-chip by tiling array (3)
Transcription profiling by RT-PCR (3)
Methylation profiling by high throughput sequencing (3)
RNA-seq of non coding RNA (3)
Animal - One-color microarray (2)
RNAi profiling by array (2)
Transcription profiling by SAGE (1)
Animal - Two-color microarray (1)
One-color microarray (1)
Transcription profiling by tiling array (1)
ChIP-chip by array (1)
Other (1)
Methylation profiling by array (1)
Proteomic profiling by array (1)
RNA-seq of coding RNA from single cells (1)
RNA-seq of total RNA (1)

Release Date

2022 (50)
2021 (49)
2013 (48)
2015 (43)
2023 (42)
2014 (42)
2020 (36)
2025 (34)
2016 (33)
2012 (33)
2011 (33)
2024 (29)
2018 (29)
2010 (29)
2019 (27)
2008 (26)
2017 (24)
2009 (18)
2007 (17)
2006 (10)
2001 (7)
2026 (6)
2003 (6)
2005 (5)
1998 (4)
2004 (2)
1999 (2)
2000 (1)

Lab affiliation

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (20)
Biognosys AG (4)
Unité de Recherche sur les Maladies Infectieuses et Tropicales Émergentes (URMITE) UMR 6236, Faculté de médecine 27 Bd Jean Moulin 13385 MARSEILLE Cedex 05 FRANCE (4)
Department of Cell & Developmental Biology, University of California, San Diego, CA 92093, USA. (3)
Department of Neurobiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA (3)
Penn State College of Medicine, Department of Medicine, Penn State Cancer Institute. (3)
Center for Biotechnology and Department of Botany, Federal University of Rio Grande do Sul, Porto Alegre, P.O. Box 15005, 91501-970, Brazil (2)
Center for Proteomics & Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA (2)
Computational Systems Biochemistry Research Group, Max-Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany (2)
Crick-GSK LinkLabs, UK (2)
Department of Immunology and Cell Biology, Sherbrooke, QC, Canada (2)
Division of Pharmacology & Toxicology, Department of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna (2)
Escola Superior de Agricultura Luiz de Queiroz da Universidade de São Paulo (2)
GSK Chair in Chemical Biology, Imperial College London Satellite Group Leader, Francis Crick Institute Founder & SAB, Myricx Bio https://myricxbio.com/ Room 301B, Molecular Sciences Research Hub, White City Campus 82 Wood Lane, London W12 0BZ, UK Tel.: 020759 + Ext. 43752 or 45821 (group) http://www.imperial.ac.uk/tate-group/ (2)
Laboratory of Mass Spectrometry, Faculty of Biotechnology, University of Wroclaw (2)
Mass Spectrometry Laboratory, Faculty of Biotechnology, University of Wroclaw (2)
Molecular Systems Immunology Group Turku Bioscience University of Turku P.O. Box 123, BioCity (Street adr. Tykistökatu 6 A, 7th floor) FIN-20521 Turku, Finland +358-40-718 4813 (Mobile) (2)
OncoProteomics Laboratory, Dept of Medical Oncology, Amsterdam University Medical Centers, Amsterdam, The Netherlands (2)
Research Centre for Genetic Engineering and Biotechnology “Georgi D Efremov”, Macedonian Academy of Sciences and Arts, Skopje, Krste Misirkov 2, 1000 Skopje, Republic of North Macedonia (2)
University of Missouri (2)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (2)
#*Assistant Professor Department of Biotechnology Indian Institute of Technology Roorkee (1)
1 - Cancer Biology & Epigenetics Group, IPO Porto Research Center (CI-IPOP), Portuguese Oncology Institute of Porto (IPO Porto), Porto, Portugal 2 - CI-IPOP @RISE-Associated Laboratory and Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC), R. Dr. António Bernardino de Almeida, Porto, Portugal (1)
1 Max Planck Fellow Group Molecular Physiology of Microbes, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany 2 Center for Synthetic Microbiology (SYNMIKRO), Marburg, Germany 3 Department of Chemistry, University of Marburg, Marburg, Germany (1)
1.Semmelweis University, Department of Pharmacology and Pharmacotherapy, Budapest, Hungary. 2.Pharmahungary Group, Szeged, Hungary (1)
1Cancer Research Program, Hospital del Mar Research Institute, Doctor Aiguader 88, Barcelona 08003, Spain. Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, Spain. (1)
1Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA 2Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, Los Angeles, CA, USA 3Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA (1)
1Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University (1)
1Integrated and Urban Plant Pathology Laboratory, University of Liège, Gembloux Agro-Bio Tech, 2 Passage des Déportés 5030 Gembloux, Belgium (1)
9McKusick-Nathans Institute of Genetic Medicine, 10Departments of Biological Chemistry, and 11Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. (1)

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High Mobility Group protein HMGB2 is a Critical Regulator of Plasmodium Oocyst Development

Two mice per group were infected with one million purified schizonts from the WT and two clones (B3 and D1) of the pyhmgb2 KO lines. Parasitemia reached 10 to 20 % and equivalent gametocytemia total RNA was extracted from the WT and the B3 and D1 clones of the KO parasite lines using the Trizol meth...

ORGANISM(S): Plasmodium yoelii

2008-04-19 | E-GEOD-9952 | biostudies-arrayexpress

Characterization of an Entamoeba histolytica High-Mobility-Group Box Protein Induced during Intestinal Infection

The unicellular eukaryote Entamoeba histolytica is a human parasite that causes amebic dysentery and liver abscess. A genome-wide analysis of gene expression modulated by intestinal colonization and invasion identified an up-regulated transcript that encoded a putative high-mobility-group box (HMGB)...

ORGANISM(S): Entamoeba histolytica

2008-11-19 | E-GEOD-12204 | biostudies-arrayexpress

A Novel Approach to Characterize the Lipidome of Marine Archaeon Nitrosopumilus maritimus by Ion Mobility Mass Spectrometry

Archaea are differentiated from the other two domains of life by their biomolecular characteristics. One such characteristic is the unique structure and composition of their lipids. Characterization of the whole set of lipids in a biological system (the lipidome) remains technologically challengi...

2021-12-16 | MTBLS3714 | MetaboLights

The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate cancer signaling pathways.

High mobility group proteins are chromatin regulators with essential functions in development, cell differentiation and cell proliferation. The protein HMG20A contains three well defined domains: an amino terminal intrinsically distorted domain, a high mobility group box with higher affinity for dou...

ORGANISM(S): Homo sapiens (Human)

2022-10-13 | PXD030769 | Pride

Cancer High mobility group proteins

High Mobility Group N proteins are required for regulation of antigen-presentation genes in macrophages

PRJNA1334290 | ENA

High Mobility Group protein mediated transcription requires DNA damage marker Î³-H2AX

The eukaryotic genome is organized into chromatin, which constitutes the physiological template for DNA-dependent processes including replication, recombination, repair and transcription. Chromatin mediated transcription regulation involves histone modifications, chromatin remodeling and DNA methyla...

ORGANISM(S): Mus musculus

2015-11-04 | E-GEOD-63861 | biostudies-arrayexpress

High Mobility Group N proteins are required for regulation of antigen-presentation genes in macrophages [RNA-seq]

PRJNA1327411 | ENA

Reciprocal regulation of cardiac chromatin by the chromatin structural proteins HMGB and CTCF

Transcriptome remodeling in heart disease occurs through the coordinated actions of transcription factors, histone modifications and other chromatin features at pathology-associated genes. It remains unknown the extent to which genome-wide chromatin reorganization also contributes to the pathologic ...

ORGANISM(S): Rattus norvegicus

2016-06-15 | E-GEOD-80453 | biostudies-arrayexpress

Comparison of the transcriptomes of hmgb1 vs Col-0

Testing the consequences of the absence of the chromatin-associated HMGB1 protein on the transcriptome in Arabidopsis. Keywords: Comparison of mutant and wildtype samples. Four replicate RNA extractions were performed of each genotype using independent pools of plants. hmgb1#1 (Cy5) vs. Col-0#1 (Cy3...

ORGANISM(S): Arabidopsis thaliana

2008-11-23 | E-GEOD-10638 | biostudies-arrayexpress

High Mobility Group protein mediated transcription requires DNA damage marker γ-H2AX

ORGANISM(S): Mus musculus

2015-11-04 | GSE63861 | GEO

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