Shotgun metagenomics, untargeted metabolomics, and targeted metabolomics of high versus normal-yield cows revealed that high-yield animals harbored distinct hindgut microbial communities enriched in bile salt hydrolase–positive taxa, and elevated levels of deoxycholic acid (DCA). Fecal microbiota...
Plant monocultures growing for extended periods face severe losses of productivity. This phenomenon, known as 'yield decline', is often caused by the accumulation of above- and below-ground plant antagonists. The effectiveness of plant defences against antagonists might help explain differences i...
Background
In large scale dairy farming systems, maintaining stable milk yield post-lactation peak is crucial for dairy farms’ economic benefits. While sufficient evidence shows the microbiota profoundly impacts host production efficiency, the specific mechanisms by which hindgut microbiota...
Clinical metabolic phenotyping employs metabolomics and lipidomics to detect and measure thousands of metabolites and lipids within human samples. This approach aims to identify metabolite and lipid changes between phenotypes (e.g. disease status) that aid understanding of biochemical mechanisms ...