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ProteomicsHigh-risk EBV promotes immune evasion in nasopharyngeal carcinoma by upregulating HLA-DP via the encoded BALF2-HR variant
Nasopharyngeal carcinoma (NPC) is prevalent in East and Southeast Asia, with genetic factors playing a significant role in its occurrence. The HLA gene region on chromosome 6 is linked to NPC susceptibility, but the mechanisms remain unclear. Epstein-Barr virus (EBV) infection is a well-established ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-17 | PXD074503 | Pride
Nasopharyngeal carcinoma Immune evasion Balf2 High-risk ebv subtype Hla-dp 
UnknownPresence of high-risk HPVs, EBV, and MMTV in human triple-negative breast cancer.
Not available
S-EPMC8828071 | biostudies-literature
TranscriptomicsTranscription profiling of human basal-like breast cancer - in vitro and in vivo Analysis of B-Myb
The basal-like breast cancer subtype portends a poor clinical prognosis, and a defining feature of this subtype is the high expression of genes in the “proliferation signature”. B-Myb, a member of the MYB protein family of transcription factors, is highly expressed in the proliferation signatur...
ORGANISM(S): Homo sapiens 
2009-01-18 | E-GEOD-11429 | biostudies-arrayexpress
TranscriptomicsHigh VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia.
High VEGFC mRNA expression of AML blasts is related to increased in vitro and in vivo drug resistance. The prognostic significance of VEGFC on long-term outcome and its associated gene expression profiles remain to be defined. We studied the effect of VEGFC on treatment outcome and investigated gene...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-22056 | biostudies-arrayexpress
UnknownInfection with human cytomegalovirus, Epstein-Barr virus, and high-risk types 16 and 18 of human papillomavirus in EGFR-mutated lung adenocarcinoma.
Not available
S-EPMC10183960 | biostudies-literature
UnknownAnalysis of NF-κB Pathway Proteins in Pediatric Hodgkin Lymphoma: Correlations with EBV Status and Clinical Outcome-A Children's Oncology Group Study.
Not available
S-EPMC6690044 | biostudies-literature
TranscriptomicsGenome-wide gene expression profiling of high-grade osteosarcoma cell lines
We performed genome-wide gene expression data of high-grade osteosarcoma cell lines, as well as on mesenchymal stem cells, and osteoblasts, and performed global test analysis in order to determine the most significantly affected KEGG pathways. Genome-wide gene expression analysis was performed on 19...
ORGANISM(S): Homo sapiens 
2013-06-06 | E-GEOD-42351 | biostudies-arrayexpress
UnknownOut-of-Africa migration and clonal expansion of a recombinant Epstein-Barr virus drives frequent nasopharyngeal carcinoma in southern China.
Not available
S-EPMC11954593 | biostudies-literature
UnknownHost genetic variants, Epstein-Barr virus subtypes, and the risk of nasopharyngeal carcinoma: Assessment of interaction and mediation.
Not available
S-EPMC10879020 | biostudies-literature
TranscriptomicsLipid metabolism genes in contralateral unaffected breast and estrogen receptor status of breast cancer
The contralateral unaffected breast of women with unilateral breast cancer (cases) is a good model for defining subtype-specific risk since women with ER-negative index primaries are at high risk for subsequent ER-negative primary cancers. We performed random fine needle aspiration (rFNA) of the una...
ORGANISM(S): Homo sapiens 
2013-03-26 | E-GEOD-41400 | biostudies-arrayexpress
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