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MetabolomicsNutritional quality and genetic differences of five amaranth cultivars revealed by metabolome profiling and whole-genome sequencing (Leaf assays)

BACKGROUND: Amaranth (Amaranthus spp.) has high nutritional quality, with edible grain and leaves, and many agronomic advantages, making it a promising part of the solution for global food insecurity. However, we lack comprehensive metabolomic and genome sequence data fo...

2025-02-25 | MTBLS3498 | MetaboLights
MetabolomicsNutritional quality and genetic differences of five amaranth cultivars revealed by metabolome profiling and whole-genome sequencing (Seed assays)

BACKGROUND: Amaranth (Amaranthus spp.) has high nutritional quality, with edible grain and leaves, and many agronomic advantages, making it a promising part of the solution for global food insecurity. However, we lack comprehensive metabolomic and genome sequence data fo...

2025-02-25 | MTBLS815 | MetaboLights
TranscriptomicsWhole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications
The needs for rapid and efficient microbial cell factory design and construction are possible through the enabling technology, metabolic engineering, which is now being facilitated by systems biology approaches. Metabolic engineering is often complimented by directed evolution, where selective press...
ORGANISM(S): Saccharomyces cerevisiae 
2010-12-22 | E-GEOD-21479 | biostudies-arrayexpress
TranscriptomicsEXPRSS: an Illumina based high-throughput expression-profiling method to reveal transcriptional dynamics - II
Background Next Generation Sequencing technologies have facilitated differential gene expression analysis through RNA-seq and Tag-seq methods. RNA-seq has biases associated with transcript lengths, lacks uniform coverage of regions in mRNA and requires 10–20 times more reads than a typical Tag-seq. ...
ORGANISM(S): Arabidopsis thaliana 
2014-06-20 | E-GEOD-51720 | biostudies-arrayexpress
TranscriptomicsIdentification and characterization of miRNAome in root, stem, leaf and tuber developmental stages of potato (Solanum tuberosum L.) by high-throughput sequencing
Purpose: MicroRNAs (miRNAs) are ubiquitous components of endogenous plant transcriptome. miRNAs are small, single-stranded and ~21 nt long RNAs which regulate gene expression at the post-transcriptional level and are known to play essential roles in various aspects of plant development and growth. P...
ORGANISM(S): Solanum tuberosum 
2014-01-09 | E-GEOD-52599 | biostudies-arrayexpress
GenomicsA genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture
Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome engineering. However, questions remain about the specificity of their target site recognition. Most previous studies have examined predicted off-target bi...
ORGANISM(S): Homo sapiens 
2015-03-04 | E-GEOD-61099 | biostudies-arrayexpress
GenomicsSequence and expression analysis of human chromosome 20 gaps
The finished human genome-assemblies comprise several hundred un-sequenced euchromatic gaps, which may be rich in long polypurine/polypyrimidine stretches. Human chromosome 20 currently has three remaining un-sequenced gaps on its q-arm. All three gaps are within gene-dense regions, or overlap loci ...
ORGANISM(S): Homo sapiens 
2012-04-17 | E-GEOD-35405 | biostudies-arrayexpress
TranscriptomicsINTEGRATIVE ONCOGENOMIC AND HIGH-THROUGHPUT SEQUENCING ANALYSES OF THE COMMONLY DELETED REGION IN CHROMOSOME 7q32 IN SPLENIC MARGINAL ZONE LYMPHOMA
This SuperSeries is composed of the following subset Series: GSE35082: INTEGRATIVE ONCOGENOMIC AND HIGH-THROUGHPUT SEQUENCING ANALYSES OF THE COMMONLY DELETED REGION IN CHROMOSOME 7q32 IN SPLENIC MARGINAL ZONE LYMPHOMA (expression) GSE35329: INTEGRATIVE ONCOGENOMIC AND HIGH-THROUGHPUT SEQUENCING ANA...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-35383 | biostudies-arrayexpress
UnknownHigh-throughput genetic engineering of nonmodel and undomesticated bacteria via iterative site-specific genome integration.
Not available
S-EPMC10005180 | biostudies-literature
TranscriptomicsEXPRSS: an Illumina based high-throughput expression-profiling method to reveal transcriptional dynamics - I
Background Next Generation Sequencing technologies have facilitated differential gene expression analysis through RNA-seq and Tag-seq methods. RNA-seq has biases associated with transcript lengths, lacks uniform coverage of regions in mRNA and requires 10–20 times more reads than a typical Tag-seq. ...
ORGANISM(S): Arabidopsis thaliana 
2014-06-20 | E-GEOD-45989 | biostudies-arrayexpress
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