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TranscriptomicsInhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2)
Monocyte chemoattractant protein 1 (MCP-1/CCL2) is critically involved in directing the migration of blood monocytes to sites of inflammation. Consequently, excessive MCP-1 secretion has been linked to many (auto)inflammatory diseases, whereas a lack of expression severely impairs immune responsiven...
ORGANISM(S): Mus musculus 
2013-04-09 | E-GEOD-43075 | biostudies-arrayexpress
TranscriptomicsWhole Transcriptome Analysis of the Silicon Response of the Diatom Thalassiosira pseudonana
Diatom cell walls, made of nanostructured silica, are of interest in diverse areas ranging from cellular structure, to hierarchical organization in biomineralization, to nanotechnology. Thus far, only cell surface proteins and proteins tightly associated with silica matrix have been characterized, a...
ORGANISM(S): Thalassiosira pseudonana CCMP1335 
2012-10-01 | E-GEOD-37081 | biostudies-arrayexpress
TranscriptomicsTranscript level coordination of carbon pathways during silicon starvation induced lipid accumulation in the diatom Thalassiosira pseudonana
Nutrient-starvation induced lipid accumulation has been reported in diverse algae, including diatoms. Molecular mechanisms underlying lipid accumulation in nutrient-starved algae are of interest to inform genetic engineering strategies aimed at improving lipid productivity. Diatom cell walls are mad...
ORGANISM(S): Thalassiosira pseudonana 
2015-12-31 | E-GEOD-75651 | biostudies-arrayexpress
UnknownMLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis.
Not available
S-EPMC7305196 | biostudies-literature
TranscriptomicsMechanisms of adaptation to stress and control of virulence in Pseudomonas aeruginosa: the OxyR regulons
Oxidative stress caused by exposure to reactive oxygen species (ROS), is a major challenge for aerobic and especially anaerobic organisms. Bacteria coordinate the response to oxidative stress through the LysR-type transcriptional regulator (LTTR) OxyR. Extensive studies have focused on the classical...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2013-12-13 | E-GEOD-33871 | biostudies-arrayexpress
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