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ProteomicsMajor determinants of airway epithelial cell sensitivity to S. aureus alpha-toxin: Disposition of toxin heptamers by extracellular vesicle formation and lysosomal degradation
Alpha-toxin is a major virulence factor of Staphylococcus aureus and plays an important role in S. aureus-induced pneumonia. Different sensitivities toward the toxin of various host cell types have been observed. In this study we investigated internalization of pore-containing areas of the plasma me...
ORGANISM(S): Homo sapiens (Human) 
2021-04-20 | PXD023678 | Pride
Cellular sensitivity Alpha-toxin Airway epithelial cells Virulence factors Staphylococcus aureus Transmembrane pores 
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