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UnknownLight-induced Nrf2-/- mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel.
Not available
S-EPMC6787253 | biostudies-literature
UnknownTransmembrane domain interactions and residue proline 378 are essential for proper structure, especially disulfide bond formation, in the human vitamin K-dependent gamma-glutamyl carboxylase.
Not available
S-EPMC2810621 | biostudies-literature
TranscriptomicsStem cell factor programs the mast cell activation phenotype
Mast cells, activated by antigen via the high affinity receptor for IgE (FcεRI), release an array of pro-inflammatory mediators that contribute to allergic disorders such as asthma and anaphylaxis. The KIT ligand, stem cell factor (SCF), is critical for mast cell expansion, differentiation and survi...
ORGANISM(S): Mus musculus 
2012-05-01 | E-GEOD-35332 | biostudies-arrayexpress
TranscriptomicsGene expression profiling upon PI3K inhibition using different inhibitors
Activation of the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is one the most frequent genetic events in human cancer. Therefore, the development of PI3K inhibitors has attracted much attention. We previously described the pyrazolopyrimidine derivative ETP-45658 as a potent inhibitor of P...
ORGANISM(S): Homo sapiens 
2014-04-08 | E-GEOD-56579 | biostudies-arrayexpress
UnknownDeveloping an Evidence-Based Interprofessional Algorithm to Apply Noninvasive Ventilation in Acute Exacerbation of COPD.
Not available
S-EPMC11580180 | biostudies-literature
ProteomicsTMT analysis of flagellum skeletons from MIP knockdown parasites
TMT data associated with Shimogawa et al. 'FAP106 is an interaction hub required for stable assembly of conserved and lineage-specific proteins at the cilium inner junction'
ORGANISM(S): Trypanosoma Brucei (ncbitaxon:5691) 
2022-11-07 | MSV000090661 | MassIVE
TranscriptomicsA Local Regulatory Network Around Three NAC Transcription Factors in Stress Responses and Senescence in Arabidopsis leaves (Botrytis cinerea infection).
A network model has been generated that describes the immediate gene expression cascade surrounding three similar but distinct NAC transcription factors that have roles to play in leaf senescence and in many stress responses in Arabidopsis. ANAC019, ANAC055 and ANAC072 belong to the same clade of N...
ORGANISM(S): Arabidopsis thaliana 
2013-04-23 | E-GEOD-45594 | biostudies-arrayexpress
UnknownMechanisms underlying differences in systemic exposure of structurally similar active metabolites: comparison of two preclinical hepatic models.
Not available
S-EPMC3083101 | biostudies-literature
TranscriptomicsTranscription profiling of human head and neck squamous cell carcinoma samples reveals a feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle
Patient selection and specimen collection. Thirty-six freshly frozen tumor samples were prospectively collected from patients undergoing surgery or biopsy for HNSCC at the University of North Carolina (UNC) at Chapel Hill (21 patients) and Vanderbilt University (15 patients). All tissues were snap-f...
ORGANISM(S): Homo sapiens 
2009-03-28 | E-GEOD-10300 | biostudies-arrayexpress
ProteomicsAPEX2 proximity proteomics of microtubule inner proteins FAP45 and FAP52
APEX2-based proximity proteomics data associated with Shimogawa et al. 'FAP106 is an interaction hub required for stable assembly of conserved and lineage-specific proteins at the cilium inner junction'
ORGANISM(S): Trypanosoma Brucei (ncbitaxon:5691) 
2022-11-07 | MSV000090660 | MassIVE
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