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ProteomicsInterferon stimulated changes in the brain phosphoproteome
Type I interferons (IFN-Is) are immunoregulatory cytokines that are essential for normal host antiviral responses. The current understanding is that IFN-Is mediate their effects through the expression of several hundred interferon-regulated genes. Here we identified a novel IFN-I response mechanism ...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-02 | PXD014443 | Pride
Astrocytes Brain Mouse Interferon Microglia Phosphoproteomics Lc-ms/ms 
ProteomicsLC-MS/MS of SETDB1 3TD after incubation with covalent ligands
In order to confirm which amino acid of the 3TD of SETDB1 is covalently modified by a set of cysteine-targeting ligands, we performed LC-MS/MS on sample containing 40 uM of SETDB1 3TD with 400 uM of ligand after overnight incubation at 4 C.
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056206 | Pride
Setdb1 Unc9846 Unc10016 Unc10013 3td Unc10014 
TranscriptomicsModeling the clinical phenotype of BTK inhibition in the mature murine immune system
Using the novel BTK inhibitor PF-303, we model the clinical phenotype of BTK inhibition by systematically examining the impact of PF-303 on the mature immune system in mice autoimmune indications. However, our current knowledge of the role of BTK in immune competence has been gathered in the context...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-56483 | biostudies-arrayexpress
GenomicsATD
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
EGAD00000000011 | EGA
GenomicsBC
WTCCC1 project Breast cancer (BC) samples
EGAD00000000013 | EGA
GenomicsMS
WTCCC1 project Multiple Sclerosis (MS) samples
EGAD00000000012 | EGA
GenomicsWTCCC2 Ankylosing spondylitis cases - individual
WTCCC1 project Ankylosing Spondylitis (AS) samples
EGAD00000000010 | EGA
Genomics58C
WTCCC1 project samples from 1958 British Birth Cohort
EGAD00000000014 | EGA
GenomicsWTCCC case-control study for Autoimmune Thyroid Disease
WTCCC genome-wide case-control association study for Autoimmune Thyroid Disease (ATD) using the 1958 British Birth Cohort collection as controls.
EGAS00000000020 | EGA
GenomicsWTCCC case-control study for Ankylosing Spondylitis
WTCCC genome-wide case-control association study for Ankylosing Spondylitis (AS) using the 1958 British Birth Cohort collection as controls.
EGAS00000000018 | EGA
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