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UnknownTwenty proteins containing a C-terminal SOCS box form five structural classes.
Not available
S-EPMC18144 | biostudies-literature
ProteomicsProteomic analyses reveal that immune integrins are major targets for proteolysis by Membrane-Associated Ring-CH (MARCH) proteins MARCH2, 3, 4 and 9.
MARCH proteins are membrane-associated Ring-CH E3 ubiquitin ligases that dampen immune responses by down-regulating cell surface expression of major histocompatibility complexes I and II as well as immune co-stimulatory receptors. We recently showed that MARCH2,3,4 and 9 also down-regulate cell surf...
ORGANISM(S): Mus musculus (Mouse) 
2021-05-07 | PXD019967 | Pride
Cell surface Integrins Immune cells 
TranscriptomicsTranscription profiling of mouse Ostes mutant soleus muscle vs wild type soleus muscles
A comparison of Ostes homozygous mutant soleus muscles to wildtype soleus muscles. Hybridisation of 3 Mouse CNG 25k oligo arrays, using 3 pools of 10 mice(5 male and 5 female) for mutant and WT.

ORGANISM(S): Mus musculus 
2009-09-17 | E-MEXP-1873 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of livers from INFgamma-/- and conditional SOCS3-/- mice treated with different cytokines to study the role of SOCS3 in IL-6 signaling pathway.
Changes in mouse liver mRNA profiles following intraperitoneal cytokine injection. Either interferon-gamma-/-, albumin-cre(-) Socs3(w/fl) mice, or albumin-cre(+) Socs3(-/fl) mice were injected with either phosphate-buffered saline, interferon-gamma, or interleukin-6, and livers taken after 4h.
ORGANISM(S): Mus musculus 
2007-11-01 | E-GEOD-369 | biostudies-arrayexpress
UnknownEmpagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10957483 | biostudies-literature
UnknownHigher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC11872607 | biostudies-literature
UnknownAzithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC7884931 | biostudies-literature
UnknownEffect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
Not available
S-EPMC7556338 | biostudies-literature
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
UnknownBaricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.
Not available
S-EPMC9333998 | biostudies-literature
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