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ProteomicsHIM-17-GFP LC-MS/MS analysis in C. elegans
HIM-17 has been implicated in the regulation of DNA double-strand break (DSB) formation during meiosis in C. elegans. In a study assessing various accessory factors involved in programmed meiotic DSB formation we show data identifying protein interactions with HIM-17 obtained by assessing HIM-17-GFP...
ORGANISM(S): Caenorhabditis elegans 
2026-01-28 | PXD057629 | Pride
Him-17 C. elegans Meiosis Lc-ms/ms 
TranscriptomicsOverlapping and separable activities of BRA-2 and HIM-17 promote occurrence and regulation of pairing and synapsis during Caenorhabditis elegans meiosis
Faithful meiotic segregation requires pairwise alignment of the homologous chromosomes and their synaptonemal complex (SC) mediated stabilization. Here, we investigate on new factors that promote and coordinate these events during C. elegans meiosis. We identify BRA-2 (BMP Receptor Associated family...
ORGANISM(S): Caenorhabditis elegans 
2025-01-22 | GSE275668 | GEO
GenomicsOverlapping and separable activities of BRA-2 and HIM-17 promote occurrence and regulation of pairing and synapsis during Caenorhabditis elegans meiosis
Overlapping and separable activities of BRA-2 and HIM-17 promote occurrence and regulation of pairing and synapsis during Caenorhabditis elegans meiosis
PRJNA1152551 | ENA
ProteomicsDistinct intersecting pathways link homolog pairing to initiation of meiotic chromosome synapsis
Faithful meiotic segregation requires pairwise alignment of the homologous chromosomes and Synaptonemal Complex assembly (SC) at their interface. Here, we investigate on new factors that promote and coordinate these events during C. elegans meiosis. We identify BRA-2 (BMP Receptor Associated family ...
ORGANISM(S): Caenorhabditis elegans 
2025-03-14 | PXD053401 | Pride
Caenorhabditis elegans Bra-2 Him-17 Lc-ms/ms 
UnknownHIM-17 regulates the position of recombination events and GSP-1/2 localization to establish short arm identity on bivalents in meiosis.
Not available
S-EPMC8092412 | biostudies-literature
UnknownOverlapping and separable activities of BRA-2 and HIM-17 promote occurrence and regulation of pairing and synapsis during Caenorhabditis elegans meiosis.
Not available
S-EPMC11906835 | biostudies-literature
OtherLarge scale transposon co-option in the Caenorhabditis germline regulatory network [longCapSeq]
The movement of repetitive elements in the germline creates widespread genomic alterations and pressure for resolution. Here we show that the Caenorhabditis clade took advantage of two transposon expansions by integrating hundreds of elements into its germline transcriptional network. We find that a...
ORGANISM(S): Caenorhabditis briggsae 
2021-12-26 | GSE192539 | GEO
TranscriptomicsLarge scale transposon co-option in the Caenorhabditis germline regulatory network [RNA-Seq]
The movement of repetitive elements in the germline creates widespread genomic alterations and pressure for resolution. Here we show that the Caenorhabditis clade took advantage of two transposon expansions by integrating hundreds of elements into its germline transcriptional network. We find that a...
ORGANISM(S): Caenorhabditis elegans 
2021-12-26 | GSE192538 | GEO
GenomicsLarge scale transposon co-option in the Caenorhabditis germline regulatory network [ChIP-Seq]
The movement of repetitive elements in the germline creates widespread genomic alterations and pressure for resolution. Here we show that the Caenorhabditis clade took advantage of two transposon expansions by integrating hundreds of elements into its germline transcriptional network. We find that a...
ORGANISM(S): Caenorhabditis elegans 
2021-12-26 | GSE192535 | GEO
GenomicsLarge scale transposon co-option in the Caenorhabditis germline regulatory network [ATAC-seq]
The movement of repetitive elements in the germline creates widespread genomic alterations and pressure for resolution. Here we show that the Caenorhabditis clade took advantage of two transposon expansions by integrating hundreds of elements into its germline transcriptional network. We find that a...
ORGANISM(S): Caenorhabditis briggsae 
2021-12-26 | GSE192534 | GEO
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