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TranscriptomicsResponse of Staphylococcus aureus to subinhibitory concentrations of a sequence-selective, DNA minor groove cross-linking pyrrolobenzodiazepine dimer.
Objectives ELB-21 is a pyrrolo[2,1-c][1,4]benzodiazepine dimer with potent antistaphylococcal activity; it binds covalently to guanine residues on opposing strands of duplex DNA, interfering with regulatory proteins and transcription elongation in a sequence-selective manner. Transcriptional and pro...
ORGANISM(S): Staphylococcus aureus 
2009-09-18 | E-BUGS-79 | biostudies-arrayexpress
UnknownPhysicochemical, Microbiological and Technological Properties of Red Deer (Cervus elaphus) Milk during Lactation.
Not available
S-EPMC8004988 | biostudies-literature
UnknownStructural insight into an evolutionarily ancient programmed cell death regulator - the crystal structure of marine sponge BHP2 bound to LB-Bak-2.
Not available
S-EPMC5386376 | biostudies-literature
UnknownBid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
Not available
S-EPMC4650538 | biostudies-literature
TranscriptomicsTranscription profiling by array of Mycobacterium tuberculosis virulent and attenuated strains infecting macrophages
Data is also available from BuG@Sbase
ORGANISM(S): Mycobacterium tuberculosis 
2010-08-16 | E-BUGS-86 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Mycobacterium avium subspecies paratuberculosis treated with rhodanine agent D157070
Data is also available from BuG@Sbase
ORGANISM(S): Mycobacterium avium 
2010-03-03 | E-BUGS-92 | biostudies-arrayexpress
UnknownAncient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis.
Not available
S-EPMC7527217 | biostudies-literature
TranscriptomicsGenetic Variation in Spatio-Temporal Confined USA300 Community-Associated MRSA Isolates: A Shift from Clonal Dispersion to Genetic Evolution?
Introduction Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are increasingly isolated, with USA300-0114 being the predominant clone in the USA. Comparative whole genome sequencing of USA300 isolates collected in 2002, 2003 and 2005 showed a limited number of single nucleo...
ORGANISM(S): Staphylococcus aureus 
2011-04-15 | E-BUGS-108 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 76 Clostridium difficile isolates to investigate clade specificity and microevolution of hypervirulent strains
Data is also available from http://bugs.sgul.ac.uk/E-BUGS-41
ORGANISM(S): Clostridium difficile 
2006-10-04 | E-BUGS-41 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of Beijing and non-Beijing Myocobacterium tuberculosis isolates from Myanmar
Background. The Beijing family of Mycobacterium tuberculosis is dominant in countries in East Asia. Genomic polymorphisms are a source of diversity within the M.tuberculosis genome and may account for the variation of virulence among M.tuberculosis isolates. To date there are no studies that have ex...
ORGANISM(S): Mycobacterium tuberculosis 
2008-09-26 | E-BUGS-66 | biostudies-arrayexpress
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