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ProteomicsCdk5r1_KO_TMT-10plex_brain_cell-autonomous_proteomics
Concerted radial migration of newly born cortical projection neurons, from their birthplace to their final target lamina, is a key step in the assembly of the cerebral cortex. The cellular and molecular mechanisms regulating radial neuronal migration in vivo are however still unclear, let alone the ...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-22 | PXD023222 | Pride
Mus musculus Brain Facs sorted 
MetabolomicsLarge neutral amino acid levels tune perinatal neuronal excitability and survival
Surprisingly little is known about the critical metabolic changes that neural cells have to undergo during development and how even mild, temporary shifts in this program can influence brain circuitries and behavior. Inspired by the discovery that mutations in SLC7A5, a transporter of metabolically-...
2023-03-28 | MTBLS6578 | MetaboLights
ProteomicsLarge neutral amino acid levels tune perinatal neuronal excitability and survival
Surprisingly little is known about the critical metabolic changes that neural cells have to undergo during development and how even mild, temporary shifts in this program can influence brain circuitries and behavior. Inspired by the discovery that mutations in SLC7A5, a transporter of metabolically ...
ORGANISM(S): Mus Musculus 
2023-02-09 | PXD038454 |
TranscriptomicsGenetic mosaic analysis of the tumorigenic process distinguishes cell of origin from cell of mutation
Cancer results from molecular mutations occurring in specific cell types, thus determining the cell-of-origin is critical for effective cancer treatment. Inferring such information from terminal tumors can be misleading because malignant tumor cells tend to acquire aberrant properties. Animal models...
ORGANISM(S): Mus musculus 
2011-07-01 | E-GEOD-26676 | biostudies-arrayexpress
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