Sort   by:  
 Page size 
TranscriptomicsRBFOX3/NeuN is required for hippocampal circuit balance and function
RBFOX3 mutations are linked to epilepsy and cognitive impairments, but the underlying pathophysiology of these disorders is poorly understood. Here we report replication of human symptoms in a mouse model with disrupted Rbfox3. Rbfox3 knockout mice displayed increased seizure susceptibility and decr...
ORGANISM(S): Mus musculus 
2016-07-26 | E-GEOD-84786 | biostudies-arrayexpress
ProteomicsPostnatal persistence of hippocampal Cajal-Retzius cells has a critical role in the establishment of the hippocampal circuit
Cajal-Retzius (CR) cells are a transient neuron type that populate the postnatal hippocampus. The role of transient cell types and circuits have been vastly addressed in neocortical regions, but poorly studied in the hippocampus. To understand how CR cells persistence influences the maturation of hi...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-24 | PXD042517 | Pride
Cajal-retzius cells Hippocampus Ca1 slm Viral vector injection Development Cell ablation Brain tissue Transgenic mouse line Hippocampal circuit Lc-ms/ms 
GenomicsCircuit and molecular architecture of a ventral hippocampal network
Circuit and molecular architecture of a ventral hippocampal network
PRJNA633892 | ENA
GenomicsSex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons
Sex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons
PRJNA885115 | ENA
UnknownLocal circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1.
Not available
S-EPMC8154026 | biostudies-literature
UnknownHippocampal neural circuit connectivity alterations in an Alzheimer's disease mouse model revealed by monosynaptic rabies virus tracing.
Not available
S-EPMC9482455 | biostudies-literature
GenomicsPostnatal persistence of hippocampal Cajal-Retzius cells has a crucial role in the establishment of the hippocampal circuit
Postnatal persistence of hippocampal Cajal-Retzius cells has a crucial role in the establishment of the hippocampal circuit
PRJNA833414 | ENA
UnknownHippocampal circuit dysfunction in psychosis.
Not available
S-EPMC9411597 | biostudies-literature
UnknownNoncanonical projections to the hippocampal CA3 regulate spatial learning and memory by modulating the feedforward hippocampal trisynaptic pathway.
Not available
S-EPMC8741299 | biostudies-literature
TranscriptomicsSex-biased effects on hippocampal circuit development by perinatal SERT expression in CA3 pyramidal neurons
We demonstrate in mice that perinatal SERT expression in glutamatergic pyramidal neurons in the hippocampus and mPFC modulates sexually dimorphic gene expression during hippocampal circuit assembly and is a source for sex-biased susceptibilities to cognitive and behavioral impairments.
ORGANISM(S): Mus musculus 
2022-10-01 | GSE214392 | GEO
Sort   by:  
 Page size