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TranscriptomicsTranscription profiling of hip1::ura4+ and slm9::ura4+ S. pombe to investigate the role of the HIRA histone chaperone complex
The assembly of nucleosomes by histone chaperones is an important component of transcriptional regulation. Here we have assessed the global roles of the S. pombe HIRA histone chaperone complex. Microarray analysis indicates that inactivation of the HIRA complex results in increased expression of at ...
ORGANISM(S): Schizosaccharomyces pombe 
2009-07-22 | E-MTAB-130 | biostudies-arrayexpress
ProteomicsProteomics of poly(ADP-ribosyl)ation uncovers a role for HIRA in the chromatin adaptation at ALT telomeres
The synthesis of poly(ADP-ribose) (PAR) reconfigures the local environment and recruits repair complexes to damaged chromatin. The degradation of PAR by PARG is essential for progression and completion of DNA repair. Here, we show that inhibition of PARG disrupts homology-directed repair (HDR) mech...
ORGANISM(S): Homo sapiens (Human) 
2020-10-12 | PXD020243 | Pride
Parps Cancer Histone Chromatin Telomere 
UnknownHIRA stabilizes skeletal muscle lineage identity.
Not available
S-EPMC8187366 | biostudies-literature
UnknownPlacing the HIRA histone chaperone complex in the chromatin landscape.
Not available
S-EPMC3974909 | biostudies-literature
UnknownHistone chaperone HIRA regulates neural progenitor cell proliferation and neurogenesis via β-catenin.
Not available
S-EPMC5496612 | biostudies-literature
UnknownThe H3.3 chaperone Hira complex orchestrates oocyte developmental competence.
Not available
S-EPMC8959146 | biostudies-literature
UnknownDifferential regulation of the histone chaperone HIRA during muscle cell differentiation by a phosphorylation switch.
Not available
S-EPMC5007640 | biostudies-literature
GenomicsDissecting regulatory pathways for transcription recovery following DNA damage reveals a non-canonical function of the histone chaperone HIRA
Dissecting regulatory pathways for transcription recovery following DNA damage reveals a non-canonical function of the histone chaperone HIRA
PRJNA637384 | ENA
UnknownThe fission yeast HIRA histone chaperone is required for promoter silencing and the suppression of cryptic antisense transcripts.
Not available
S-EPMC2738286 | biostudies-literature
UnknownThe HIRA complex that deposits the histone H3.3 is conserved in Arabidopsis and facilitates transcriptional dynamics.
Not available
S-EPMC4163656 | biostudies-literature
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