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TranscriptomicsTranscriptional profiles of Ad-F3 and Ad-F7 transduced macrophages
To identify genes that may regulate distinct or overlapping functions of IRF-3 and IRF-7, primary human macrophage preparations were transduced with adenoviral vectors: Ad-GFP (control), Ad-F3 (expressing the active form of IRF-3, IRF-3 5D), or Ad-F7 (expressing the active form of IRF-7, IRF-7 D247-...
ORGANISM(S): Homo sapiens 
2008-11-29 | E-GEOD-11926 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles of Ad-F7 transduced macrophages treated with anti-IFNAR2 antibody or control isotype (IgG)
Determine the role of interferons in the transcriptional profile of Ad-F7 transduced primary human macrophages using neutralizing antibody for the type I IFN receptor (IFNAR2). Primary human macrophage preparations were transduced with Ad-GFP or Ad-F7 and treated with control isotype (IgG) or neu...
ORGANISM(S): Homo sapiens 
2008-11-29 | E-GEOD-12002 | biostudies-arrayexpress
TranscriptomicsTranscriptional re-programming of primary human macrophages by IRF-3 and IRF-7
This SuperSeries is composed of the following subset Series: GSE11926: Transcriptional profiles of Ad-F3 and Ad-F7 transduced macrophages. GSE12002: Transcriptional profiles of Ad-F7 transduced macrophages in the presence of neutralizing antibody for the type I interferon receptor (IFNAR2) or contr...
ORGANISM(S): Homo sapiens 
2008-11-29 | E-GEOD-12120 | biostudies-arrayexpress
TranscriptomicsSystems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-60574 | biostudies-arrayexpress
UnknownHostile takeovers: viral appropriation of the NF-kappaB pathway.
Not available
S-EPMC199181 | biostudies-literature
UnknownDifferential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7.
Not available
S-EPMC2698742 | biostudies-literature
UnknownType I Interferons in COVID-19 Pathogenesis.
Not available
S-EPMC8468334 | biostudies-literature
UnknownMicroarray comparative genomic hybridisation analysis of intraocular uveal melanomas identifies distinctive imbalances associated with loss of chromosome 3.
Not available
S-EPMC2361503 | biostudies-literature
UnknownFighting HIV-1 Persistence: At the Crossroads of "Shoc-K and B-Lock".
Not available
S-EPMC8622007 | biostudies-literature
TranscriptomicsGenes regulated in EML1 cells expressing the TEL-AML1 oncogene after 5 and 7 days of treatment with IL7 and FLT3 ligand.
The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene, which functions as a transcription factor. TEL-AML1 expression in EML1 cells results in an impairment of differentiation along the B-lymphoi...
ORGANISM(S): Mus musculus 
2015-05-13 | E-GEOD-64919 | biostudies-arrayexpress
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