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Genome-wide analysis of gene expression after stimulation with histamine to assess the main processes, molecular functions and cellular components affected as well as genes related to skin barrier function. HaCaT cells were exposed to histamine (1ug/ml) for 24h. The cells were lysed, total RNA was ...
ORGANISM(S): Homo sapiens 
Confluent human umbilical vein endothelial cells (HUVECs) were exposed to histamine (100 mM) for 2 hours. Ribosomal profiling via gradient centrifugation and fractionation was used to separate monosome, or under-translated, and polysome, or actively translated, mRNA species that were then used to p...
ORGANISM(S): Homo sapiens 
We previously showed that transgenic enhancement of histamine production in B16-F10 melanomas strongly supports tumor growth in C57Bl/6 mice (Cancer Res, 2005 Pos et al.). In this array experiment, gene expression profiles of transgenic mouse melanomas, secreting different amounts of histamine, were...
ORGANISM(S): Mus musculus 
Immunoglobulin (Ig) E-mediated activation of mast cells and basophils underlies allergic diseases such as asthma. Histamine-releasing factor (HRF), also known as translationally controlled tumor protein (TCTP) and fortilin, is a highly conserved protein with both intracellular and extracellular func...
ORGANISM(S): Mus musculus 
Effect of depletion of histamine receptor HRH1 on gene expression of histamine treated human endothelial cells
Endothelial cells (HUVEC) were treated with histamine, the endogenous ligand of histamine receptors, for a global overview of its cellular effects. Changes of the intracellular and secreted proteomes were analyzed using shotgun proteomics. Furthermore, a selected set of proteins was quantified using...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-02-28 | MSV000080587 | MassIVE
Histamine receptor antagonists, commonly used to treat allergies, block histamine signalling and have been shown to impair acute and chronic adaptations to high-intensity and endurance-type exercise. Since it remains unclear whether this is a universal mechanism of muscle adaptation, this study inve...
ORGANISM(S): Homo sapiens (Human) 
2026-03-04 | PXD064353 | Pride
This SuperSeries is composed of the following subset Series: GSE4919: Translation State Array Analysis of Thrombin Stimulated Human Endothelial Cells GSE5352: Translation State Array Analysis of LPS Stimulated Human Endothelial Cells GSE5353: Translation State Array Analysis of Insulin Stimulated Hu...
ORGANISM(S): Homo sapiens 
Allergic mediator histamine confers immunotherapy resistance in cancer patients via histamine receptor 1 on macrophage
Mast Cell Derived Histamine Negatively Regulates Hematopoiesis
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