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UnknownAnti-cancer effects of the HuR inhibitor, MS-444, in malignant glioma cells.
Not available
S-EPMC6606032 | biostudies-literature
UnknownIGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling.
Not available
S-EPMC6148802 | biostudies-literature
UnknownDevelopment of a Sox2 reporter system modeling cellular heterogeneity in glioma.
Not available
S-EPMC4483103 | biostudies-literature
UnknownDeletion of the RNA regulator HuR in tumor-associated microglia and macrophages stimulates anti-tumor immunity and attenuates glioma growth.
Not available
S-EPMC7008520 | biostudies-literature
UnknownNew quantitative approach reveals heterogeneity in mitochondrial structure-function relations in tumor-initiating cells.
Not available
S-EPMC6526706 | biostudies-literature
ProteomicsEndothelial-secreted Endocan protein activates PDGFRa signaling and regulates vascularity, radioresistance, and regional phenotype in glioblastoma
Extensive neovascularization is a hallmark of glioblastoma (GBM). In addition to supplying oxygen and nutrients, vascular endothelial cells provide trophic support to GBM cells via paracrine signaling. Here we report that Endocan (ESM1), an endothelial-secreted proteoglycan, confers enhanced prolife...
ORGANISM(S): Homo sapiens (Human) 
2024-12-04 | PXD057635 | Pride
Brain cancer  glioma  glioblastoma  endocan  esm1  pdgfra  myc  angiogenesis  endothelial cells  radioresistance 
UnknownProtein Kinase D1 Signaling in Cancer Stem Cells with Epithelial-Mesenchymal Plasticity.
Not available
S-EPMC9739736 | biostudies-literature
TranscriptomicsExpression data from human glioma cancer stem cell (CSC) specimens following knockdown of GREM1
CSCs differentially secrete the BMP antagonist Gremlin1 compared to non-stem glioma populations. Knockdown of Gremlin1 decreases CSC proliferation and tumorigenicity, establishing Gremlin1 as an essential effector for CSC maintenance. We used a microarray to determine the gene expression programs t...
ORGANISM(S): Homo sapiens 
2014-06-03 | E-GEOD-52846 | biostudies-arrayexpress
UnknownAddition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo.
Not available
S-EPMC5752277 | biostudies-literature
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