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Deep RNA sequencing analysis after Malat1 silencing in mouse HL1 cells
The aim of the experiment was to identify genome wide binding sites for Gata4, Mef2a, Nkx2.5, Srf, p300, Pol_II, H3ac, H3K4me1 by using Chromatin Immunoprecipitation followed by microarray analysis (ChIP-chip) in HL1 cells.
ORGANISM(S): Mus musculus 
We investigated the cardiac transcription network driven by the DNA-binding key factor Srf in combination with epigenetic marks of histone 3 acetylation (H3ac). Srf has been shown to play a key role in cardiac cell growth and muscle gene regulation. However, we still have limited understanding of th...
ORGANISM(S): Mus musculus 
Human Hela and murine HL1 cells were cultured and infected in vitro with C3 protease and inactive mutant protease. Cellular proteomes were collected, labeled by isotopic dimethylation and N-terminal peptides were enriched using TALS proteomics.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2018-03-05 | PXD008718 | Pride
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