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TranscriptomicsCD8 T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles [dataset 1]
Few non-classical HLA-E restricted HIV-specific epitopes have been described, and even less is known about the functional profile of responding CD8 T cells (CD8s). This study evaluates the functional characteristics of CD8s targeting the Gag epitope (KAFSPEVIPMF or KF11) based on their restriction b...
ORGANISM(S): Homo sapiens 
2025-12-11 | GSE306022 | GEO
TranscriptomicsCD8 T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles [dataset 2]
Few non-classical HLA-E restricted HIV-specific epitopes have been described, and even less is known about the functional profile of responding CD8 T cells (CD8s). This study evaluates the functional characteristics of CD8s targeting the Gag epitope (KAFSPEVIPMF or KF11) based on their restriction b...
ORGANISM(S): Homo sapiens 
2025-12-11 | GSE306023 | GEO
ProteomicsHLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis
Autoimmune diseases are often associated with HLA molecules. Multiple sclerosis (MS) is a prototypical example with the HLA-DR15 haplotype as strongest genetic factor. How it contributes to MS is not clear, but key to understand this and other autoimmune diseases. Autoreactive CD4+ T cells and proin...
ORGANISM(S): Homo sapiens (Human) 
2020-10-22 | PXD015249 | Pride
Multiple sclerosis Hla cross-restriction Immunopeptidome B cells Hla-dr-derived self-peptides Cross-reactivity Hla-dr15 molecules Autoreactive cd4+ t cells 
GenomicsCD8 T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles [dataset 2]
CD8 T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles [dataset 2]
PRJNA1308970 | ENA
GenomicsCD8 T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles [dataset 1]
CD8 T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles [dataset 1]
PRJNA1308967 | ENA
UnknownMagnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction.
Not available
S-EPMC8039299 | biostudies-literature
UnknownThe effect of HLA polymorphisms on the recognition of Gag epitopes in HIV-1 CRF01_AE infection.
Not available
S-EPMC3407236 | biostudies-literature
UnknownCross-HLA targeting of intracellular oncoproteins with peptide-centric CARs.
Not available
S-EPMC8599005 | biostudies-literature
UnknownActivation of Human CD8+ T Cells with Nitroso Dapsone-Modified HLA-B*13:01-Binding Peptides.
Not available
S-EPMC7614401 | biostudies-literature
UnknownUnderstanding the Role of HLA Class I Molecules in the Immune Response to Influenza Infection and Rational Design of a Peptide-Based Vaccine.
Not available
S-EPMC9695287 | biostudies-literature
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