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Specialized chromatin-binding proteins are required for DNA-based processes during development. We recently established PWWP2A as a direct histone variant H2A.Z interactor involved in mitosis and craniofacial development. Here, we identify the H2A.Z/PWWP2A-associated protein HMG20A as part of severa...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD038968 | Pride
Transcriptome analysis upon Hmg20a knockdown in astrocytes
We recently demonstrated that the ‘Metabesity’ factor HMG20A is essential for beta cell functional maturity and adaptation to physiological stress. As this chromatin remodeling factor also dictates CNS development, we sought to determine whether HMG20A is expressed in astrocytes and whether it poten...
ORGANISM(S): Mus musculus 
2021-06-09 | GSE161334 | GEO
High mobility group proteins are chromatin regulators with essential functions in development, cell differentiation and cell proliferation. The protein HMG20A contains three well defined domains: an amino terminal intrinsically distorted domain, a high mobility group box with higher affinity for dou...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD030769 | Pride
Transcriptome analysis upon PHF14 and HMG20A knockdown in MDA-MB-231 cells
The H2A.Z.1/PWWP2A/NuRD-associated protein HMG20A controls early head and heart developmental transcription programs [HeLa_RNA_AH]
The H2A.Z.1/PWWP2A/NuRD-associated protein HMG20A controls early head and heart developmental transcription programs [HeLa_ChIP_AH]
The H2A.Z.1/PWWP2A/NuRD-associated protein HMG20A controls early head and heart developmental transcription programs [CNR_CM_AH]
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