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TranscriptomicsExpression data of Hmg20 knock down I/11 cells and controls
We performed microarray analysis to investigate the gene expression profile changes induced by Hmg20b knock down in I/11 cells. Three normal and three Hmg20b knocked down I/11 cell Samples were examined.
ORGANISM(S): Mus musculus 
2011-10-18 | E-GEOD-29169 | biostudies-arrayexpress
ProteomicsHMG20B stabilizes interaction of LSD1 with GFI1 on chromatin to confer 1 transcription repression and leukemia cell differentiation block
Pharmacologic inhibition of LSD1 induces molecular and morphologic differentiation of blast cells in acute myeloid leukaemia (AML) patients harboring MLL gene translocations. In addition to its demethylase activity, LSD1 has a critical scaffolding function at genomic sites occupied by the SNAG domai...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD030581 | Pride
Human ltq orbitrap velos 
UnknownA cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis.
Not available
S-EPMC4614378 | biostudies-literature
UnknownHMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block.
Not available
S-EPMC7613766 | biostudies-literature
UnknownA mitotic function for the high-mobility group protein HMG20b regulated by its interaction with the BRC repeats of the BRCA2 tumor suppressor.
Not available
S-EPMC3145889 | biostudies-literature
GenomicsHMG20B stabilizes interaction of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block [ChIP-seq I]
HMG20B stabilizes interaction of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block [ChIP-seq I]
PRJNA793917 | ENA
GenomicsHMG20B stabilizes interaction of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block [RNA-seq]
HMG20B stabilizes interaction of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block [RNA-seq]
PRJNA793915 | ENA
UnknownCPSF4-mediated regulation of alternative splicing of HMG20B facilitates the progression of triple-negative breast cancer.
Not available
S-EPMC11673668 | biostudies-literature
GenomicsHMG20B stabilizes interaction of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block [ChIP-seq II]
HMG20B stabilizes interaction of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block [ChIP-seq II]
PRJNA793916 | ENA
TranscriptomicsHMG20B stabilizes interaction of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block [RNA-seq]
Pharmacologic inhibition of LSD1 induces molecular and morphologic differentiation of blast cells in acute myeloid leukaemia (AML) patients harboring MLL gene translocations. In addition to its demethylase activity, LSD1 has a critical scaffolding function at genomic sites occupied by the SNAG domai...
ORGANISM(S): Homo sapiens 
2022-10-06 | GSE192974 | GEO
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