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TranscriptomicsExpression data from TGFbeta-treated control or aPKC silenced A549 cells
Aberrant TGFbeta signalling is a hallmark of epithelial derived tumours. Signalling patterns can depend on the membrane trafficking and internalization of the TGFbeta receptors. Protein kinase C (PKC), particularly the atypical PKC isoforms, alter the trafficking of TGFbeta receptors and can alter T...
ORGANISM(S): Homo sapiens 
2011-01-29 | E-GEOD-26241 | biostudies-arrayexpress
UnknownStudy protocol for a pilot randomized, double-blind, placebo-controlled trial to investigate the anti-inflammatory effects of Frondanol in adults with inflammatory bowel disease.
Not available
S-EPMC9760652 | biostudies-literature
TranscriptomicsSynergism between Activin A and BMP4 in directing the formation of definitive endoderm in human embryonic stem cells
Human embryonic stem cells (HESCs) herald tremendous promise for the production of clinically useful cell types for the treatment of injury and disease. Numerous reports demonstrate their differentiation into definitive endoderm (DE) cells, the germ layer from which pancreatic β cells and hepatocyte...
ORGANISM(S): Homo sapiens 
2011-11-10 | E-GEOD-30630 | biostudies-arrayexpress
UnknownNerolidol Mitigates Colonic Inflammation: An Experimental Study Using both In Vivo and In Vitro Models.
Not available
S-EPMC7400891 | biostudies-literature
UnknownUsing syndromic measures of mortality to capture the dynamics of COVID-19 in Java, Indonesia, in the context of vaccination rollout.
Not available
S-EPMC8212796 | biostudies-literature
TranscriptomicsPhenotypic plasticity determines cancer stem cell therapeutic resistance in oral squamous cell carcinoma II
Cancer stem cells (CSCs) drive tumour spread and therapeutic resistance, and can undergo epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET) to switch between epithelial and post-EMT sub-populations. Examining oral squamous cell carcinoma (OSCC), we now show tha...
ORGANISM(S): Homo sapiens 
2016-01-12 | E-GEOD-74580 | biostudies-arrayexpress
TranscriptomicsCapsule Mediates the Cell Shape of pcsB Mutants in Serotype 2 Streptococcus pneumoniae
PcsB is a protein of unknown function that plays a critical role in cell division in Streptococcus pneumoniae and other ovococcus species of Streptococcus. We constructed isogenic sets of mutants expressing different amounts of PcsB in laboratory strain R6 and virulent serotype 2 strain D39 to evalu...
ORGANISM(S): Streptococcus pneumoniae 
2010-05-22 | E-GEOD-13107 | biostudies-arrayexpress
TranscriptomicsRNA-seq time-course of Calu-3 cells infected with SARS-CoV-2 early-lineage and Alpha variant viruses
Emergence of SARS-CoV-2 variants of concern (VOCs), including the globally successful Alpha (B.1.1.7) variant, suggests viral adaptation to enhance human-to-human transmission. Although much effort has focused on characterisation of spike changes, Alpha mutations outside spike likely contribute to a...
ORGANISM(S): Homo sapiens 
2021-12-31 | E-MTAB-11275 | biostudies-arrayexpress
UnknownEffect of Cangrelor on Infarct Size in ST-Segment-Elevation Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention: A Randomized Controlled Trial (The PITRI Trial).
Not available
S-EPMC11224569 | biostudies-literature
UnknownAntiplatelet therapy and the effects of B vitamins in patients with previous stroke or transient ischaemic attack: a post-hoc subanalysis of VITATOPS, a randomised, placebo-controlled trial.
Not available
S-EPMC3361667 | biostudies-literature
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