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TranscriptomicsMeiotic time-course expression profile
To investigate the dynamics of the meiotic transcriptome and to ensure meiotic synchrony of our samples, we measured RNA abundance in vegetative cells, respiratory (pre-meiotic) cells and in synchronously sporulating cells at various times after transfer to sporulation media (SM). SK1 yeast strain S...
ORGANISM(S): Saccharomyces cerevisiae SK1 
2010-05-22 | E-GEOD-18181 | biostudies-arrayexpress
GenomicsPlasma DNA - GIS
Data Access Committee EGAC00001001733
EGAC00001001733 | EGA
TranscriptomicsDNA double-strand breaks and 3D chromatin conformation (Hi-C, 4C-seq, ChIP-seq)
DNA Double-Strand Breaks (DSBs) are highly detrimental since they can lead to mutations and chromosomes rearrangements (amplification, deletion, translocation and chromosome loss). Here, we set to assess the tridimensional genome organization around DSBs and its role in DSB repair foci formation. We...
ORGANISM(S): Homo sapiens 
2021-01-29 | E-MTAB-8851 | biostudies-arrayexpress
MetabolomicsSymbiotic bacteria-derived organic acids protect Delia antiqua larvae from entomopathogenic fungal infection

The protection of associated microbiota for their animal hosts against pathogen infection has been studied widely over the last 100 years. However, how those microbes protect the animal host is limitedly investigated. In former studies, body surface microbes of one insect, Delia antiqua,...

2020-11-12 | MTBLS2074 | MetaboLights
TranscriptomicsTranscription profiling by array of human renal proximal tubular cell cultures treated with nephrotoxins
This experiment is designed to investigate common transcriptional alterations in renal proximal tubular cell cultures due to nephrotoxin exposure.
ORGANISM(S): Homo sapiens 
2011-02-01 | E-MEXP-2599 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis roots and shoots in response to hypoxia using immunopurified mRNA-ribosome complexes
Plant organs are comprised of distinct cell types with unique assemblages of mRNAs. This is a collection of CEL files of mRNA profiles of the total steady-state mRNAs and polysomal mRNAs of distinct cell types of the whole root and shoot of 7-d-old Arabidopsis thaliana seedlings. The cell type speci...
ORGANISM(S): Arabidopsis thaliana 
2009-10-16 | E-GEOD-14502 | biostudies-arrayexpress
ProteomicsSerum integrative omics reveals the landscape of human diabetic kidney disease
Diabetic kidney disease (DKD) is the most common microvascular complication of type 2 diabetes mellitus (2-DM). Currently, urine and kidney biopsy specimens are the major clinical resources for DKD diagnosis. The diagnostic values of blood in monitoring the onset and progression of DKD have not been...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-22 | MSV000087487 | MassIVE
UnknownClonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4.
Not available
S-EPMC10089623 | biostudies-literature
TranscriptomicsArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
RELEVANCE: Smith-Lemli-Opitz syndrome (SLOS) is a human disease caused by mutations in the gene coding for the enzyme DHCR7 (7-dehydrocholesterol (7DHC) reductase), which catalyzes the final step of cholesterol biosynthesis. Accumulated 7DHC in tissues and body fluids of SLOS patients gives rise t...
ORGANISM(S): Mus musculus 
2021-03-20 | E-MTAB-10055 | biostudies-arrayexpress
UnknownA high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain.
Not available
S-EPMC10719114 | biostudies-literature
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