Sort   by:  
 Page size 
MetabolomicsAggressive breast cancers secrete heme metabolites to alter macrophage immune suppression and function
The heme catabolism pathway is often elevated in aggressive cancers; however, the impact of this pathway and some of its byproducts on the tumor microenvironment remain largely unknown. In human breast cancers, tumor expression of the heme catabolizing enzyme heme oxygenase-1 (HO-1/HMOX1) is positiv...
2026-04-24 | MTBLS14278 | MetaboLights
TranscriptomicsCigarette Smoking Induces Small Airway Epithelial Epigenetic Changes with Corresponding Modulation of Gene Expression
The small airway epithelium (SAE), the first site of smoking-induced lung pathology, exhibits genome-wide changes in gene expression in response to cigarette smoking. Based on the increasing evidence that the epigenome can respond to external stimuli in a rapid manner, we assessed the SAE of smokers...
ORGANISM(S): Homo sapiens 
2013-08-05 | E-GEOD-43079 | biostudies-arrayexpress
TranscriptomicsTranscriptional responses of sympathetic neurons during BMP-induced primary dendritogenesis
The objective of this study was to identify genes that are differentially regulated in cultured sympathetic neurons during BMP-induced dendritic growth and to determine the temporal expression patterns of these genes. We determined that inhibiting transcription within the first 24 hours after adding...
ORGANISM(S): Rattus norvegicus 
2011-06-30 | E-GEOD-28150 | biostudies-arrayexpress
MetabolomicsGut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
UnknownHuman leukocyte antigen allele and haplotype frequencies in Singapore bone marrow donors and cord blood units.
Not available
S-EPMC9873421 | biostudies-literature
UnknownExpansion, persistence, and efficacy of donor memory-like NK cells infused for posttransplant relapse.
Not available
S-EPMC9151697 | biostudies-literature
TranscriptomicsGenes involved in thoracic exoskeleton formation during the pupal-to-adult molt of a social insect model, Apis mellifera
The exoskeleton gives to insects its shape, waterproofing and a range of other roles, besides serving as means of locomotion, the motor function being accomplished by the attachment of somatic muscles. Exoskeleton is renewed every time the insect molts under the control of ecdysteroid hormones. The ...
ORGANISM(S): Apis mellifera 
2012-12-29 | E-GEOD-43047 | biostudies-arrayexpress
TranscriptomicsExpression data from C2C12 cells with or without Smad3 overexpression
The goal of this study was to identify genes in C2C12 myoblasts whose expression was altered by overexpression of Smad3. Four total samples were analyzed. Two biological replicates were prepared from C2C12 cells infected with retroviral vector encoding wildtype Smad3 and exposed for 24 hours to 100 ...
ORGANISM(S): Mus musculus 
2011-10-20 | E-GEOD-30459 | biostudies-arrayexpress
TranscriptomicsAlcohol-free fermented berry beverage phenolics attenuate diet-induced obesity and blood glucose in C57BL/6J mice
The objectives of this study were to understand the effect of phenolic compounds from fermented berry beverages on hyperglycemia and obesity in vivo using mice fed a high fat diet. Our hypothesis was that consumption of a fermented blueberry-blackberry beverage and its phenolic compounds would reduc...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-74008 | biostudies-arrayexpress
TranscriptomicsIllumina Infinium HumanMethylation450 BeadChip profiling of paediatric high grade gliomas and diffuse intrinsic pontine gliomas
We have used Illumina Infinium HumanMethylation450 BeadChip array profiling to profile paediatric high grade gliomas and diffuse intrinsic pontine gliomas. The 450K methylation array is being used to separate brain tumour samples on the basis of their methylation profiles which represent the cell of...
ORGANISM(S): Homo sapiens 
2017-09-28 | E-MTAB-5528 | biostudies-arrayexpress
Sort   by:  
 Page size