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ProteomicsRobust micro-flow LC-MS/MS for proteome analysis – 38,000 runs and counting
Micro-flow liquid chromatography tandem mass spectrometry (µLC–MS/MS) is increasingly becoming an alternative to nano-LC–MS/MS for the analysis of proteomes. We have recently demonstrated the potential of a µLC–MS/MS system operating with a 1 mm i.d. × 150 mm column and at a flow rate of 50 µl/min f...
ORGANISM(S): Homo sapiens (Human) 
2021-02-22 | PXD023650 | Pride
Micro-flow lc Plasma Proteomics Urine 1.0 mm id column 
TranscriptomicsRegulation of Trypanosoma brucei total and polysomal mRNA during development within its mammalian host
The gene expression of Trypanosoma brucei has been examined extensively in the blood of mammalian hosts and in forms found in the midgut of its arthropod vector, the tsetse fly. However, trypanosomes also undergo development within the mammalian bloodstream as they progress from morphologically M-bM...
ORGANISM(S): Trypanosoma brucei brucei 
2013-12-16 | E-GEOD-46388 | biostudies-arrayexpress
UnknownIFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury.
Not available
S-EPMC5397848 | biostudies-literature
TranscriptomicsMurine hindlimb tissue: ischemic vs. control
Unilateral femoral artery occlusion (right side) and a sham operation on the contralateral (left) side was performed in C57BL/6J mice under anesthesia by double ligation of the superficial femoral artery proximal to the deep femoral artery and distal femoral artery. Animal numbers are stated with th...
ORGANISM(S): Mus musculus 
2015-06-12 | E-GEOD-63212 | biostudies-arrayexpress
TranscriptomicsContrast of poly-ribosomal mRNA in germina vesicle (GV) and metaphase II (MII) bovine oocytes.
Poly-ribosomal mRNA from pools of 75 bovine oocytes at the germinal vesicle(GV) and metaphase II(MII) stages were isolated by sucrose fractionation then compared through microarray hybridization. 3 biological replicates from germinal vesicle(GV) and metaphase II(MII) bovine oocytes were hybridized a...
ORGANISM(S): Bos taurus 
2014-09-09 | E-GEOD-56603 | biostudies-arrayexpress
UnknownArsenic redox transformations and cycling in the rhizosphere of Pteris vittata and Pteris quadriaurita.
Not available
S-EPMC7610922 | biostudies-literature
ProteomicsHoxa9 and Meis1 cooperatively induce addiction to Syk signaling by suppressing miR-146a in acute myeloid leukemia
The transcription factor Meis1 drives myeloid leukemogenesis in the context of Hox gene overexpression but is currently considered undruggable. We therefore investigated whether myeloid progenitor cells transformed by Hoxa9 and Meis1 become addicted to targetable signaling pathways. A comprehensive ...
ORGANISM(S): Mus musculus (Mouse) 
2017-06-14 | PXD004192 | Pride
Mass spectrometry Transcriptomics Phosphoproteomics Acute myeloid leukemia 
UnknownCombination of methamphetamine and HIV-1 gp120 causes distinct long-term alterations of behavior, gene expression, and injury in the central nervous system.
Not available
S-EPMC4370186 | biostudies-literature
TranscriptomicsImpact of sucrose retrieval upon ex vitro acclimatization
Hybridization and study was conducted to measure the impact of short-term sugar deprivation, on an acclimatization time-scale, imposed to plantlet transferred from in vitro to ex vitro culture conditions. We thus submitted in vitro tomato plantlets to sugar deprivation for 24-h in order to better un...
ORGANISM(S): Solanum lycopersicum 
2010-05-16 | E-GEOD-14061 | biostudies-arrayexpress
TranscriptomicsmiRNA transcription profiling in Status Epilepticus Induced Epileptogenic Process
miRNA array comparing the transcription profile of control rats and rats after intra-hippocampal pilocarpine-induced Status Epilepticus (PILO-SE).
ORGANISM(S): Rattus norvegicus 
2016-04-28 | E-MTAB-4633 | biostudies-arrayexpress
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