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TranscriptomicsMatrix Elasticity Does Not Affect Replicative Senescence or DNA Methylation Patterns of Mesenchymal Stem Cells [DNAm profiling]
Matrix elasticity influences differentiation of mesenchymal stem cells (MSCs) but it is unclear if these effects are only transient - while the cells reside on the substrate - or if they reflect persistent lineage commitment. In this study, MSCs were continuously culture-expanded in parallel either ...
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-55888 | biostudies-arrayexpress
TranscriptomicsSurface Topography Enhances Differentiation of Mesenchymal Stem Cells Towards Osteogenic and Adipogenic Lineages
Surface topography impacts on cell growth and differentiation, but it is not trivial to generate homogeneous surface structures and to define the specific morphological parameters of relevance. In this study, we have compared gene expression profiles of mesenchymal stem cells (MSCs) on nanostructure...
ORGANISM(S): Homo sapiens 
2015-08-25 | E-GEOD-61113 | biostudies-arrayexpress
TranscriptomicsMatrix Elasticity Does Not Affect Replicative Senescence or DNA Methylation Patterns of Mesenchymal Stem Cells [gene expression profiling]
Matrix elasticity influences differentiation of mesenchymal stem cells (MSCs) but it is unclear if these effects are only transient - while the cells reside on the substrate - or if they reflect persistent lineage commitment. In this study, MSCs were continuously culture-expanded in parallel either ...
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-55867 | biostudies-arrayexpress
TranscriptomicsOsmotic regulation of hepatic choline metabolism
Betaine critically contributes to the control of hepatocellular hydration and provides protection of the liver from different kinds of stress. This study investigates to what extent hepatocellular hydration changes affect the expression levels of enzymes involved in the metabolism of betaine and rel...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-42275 | biostudies-arrayexpress
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