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UnknownMonomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit.
Not available
S-EPMC1904172 | biostudies-literature
TranscriptomicsTranscription profiling of primary human prostate cancer-associated fibroblasts
Primary human prostate fibroblast cultures were generated via an explant culture method from 4mm biopsies taken from radical prostatectomy samples of treatment-naive prostate cancer patients. The samples include partially patient-matched fibroblast cultures from benign- as well as cancer-associated ...
ORGANISM(S): Homo sapiens 
2025-09-02 | E-MTAB-13167 | biostudies-arrayexpress
UnknownNegative electrostatic potentials in a Hofmann-type metal-organic framework for efficient acetylene separation.
Not available
S-EPMC9489771 | biostudies-literature
MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
UnknownExplicit spatiotemporal simulation of receptor-G protein coupling in rod cell disk membranes.
Not available
S-EPMC4156778 | biostudies-literature
UnknownRole of Structural Dynamics at the Receptor G Protein Interface for Signal Transduction.
Not available
S-EPMC4659624 | biostudies-literature
UnknownTetrakis-Cyanoacetylides as Building Blocks for a Second Generation of Spin-Switchable Hofmann-type Networks with Enhanced Porosity.
Not available
S-EPMC11409210 | biostudies-literature
UnknownCrystal structure of a common GPCR-binding interface for G protein and arrestin.
Not available
S-EPMC4199108 | biostudies-literature
MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
UnknownSignal transfer from rhodopsin to the G-protein: evidence for a two-site sequential fit mechanism.
Not available
S-EPMC21788 | biostudies-literature
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