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TranscriptomicsGenome-wide analyses of GATA6 occupancy and functions provide insights into its oncogenic mechanisms in human gastric cancer (microarray)
To identifiy core GATA6 functions and transcriptional targets in human gastric cancer, including additional subservient transcriptional regulators via integrative analysis of GATA6 transcription factor occupancy, gene dependency, and tumor synexpression. This study used Affymetrix U133A 2.0 gene chi...
ORGANISM(S): Homo sapiens 
2013-12-02 | E-GEOD-43196 | biostudies-arrayexpress
GenomicsGenome-wide analyses of GATA6 occupancy and functions provide insights into its oncogenic mechanisms in human gastric cancer [ChIP-Seq]
To identifiy core GATA6 functions and transcriptional targets in human gastric cancer, including additional subservient transcriptional regulators via integrative analysis of GATA6 transcription factor occupancy, gene dependency, and tumor synexpression. Transcription factor binding site identificat...
ORGANISM(S): Homo sapiens 
2013-12-02 | E-GEOD-51936 | biostudies-arrayexpress
TranscriptomicsTranscriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer fatalities in Western societies, characterized by high metastatic potential and resistance to chemotherapy. Critical molecular mechanisms of these phenotypical features still remain unknown, thus hampering the development ...
ORGANISM(S): Homo sapiens 
2015-06-16 | E-GEOD-59761 | biostudies-arrayexpress
TranscriptomicsPaternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (small RNA)
Characterized the small (19-35 bp) RNA population from control and low protein offspring livers by high throughput sequencing. Eight sequencing lanes, one for each animal, with an average of 3.7 million mappable reads per lane. A number of miRNAs changed expression in the offspring from low protein ...
ORGANISM(S): Mus musculus 
2011-01-14 | E-GEOD-25897 | biostudies-arrayexpress
TranscriptomicsPaternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals
This SuperSeries is composed of the following subset Series: GSE25895: Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (dye swap) GSE25896: Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammal...
ORGANISM(S): Mus musculus 
2011-01-14 | E-GEOD-25899 | biostudies-arrayexpress
TranscriptomicsCaM Kinase II mediates maladaptive post-infarct remodeling but not acute myocardial ischemia/reperfusion injury
Calcium/calmodulin-dependent protein kinase II (CaMKII) was suggested to mediate ischemic myocardial injury and adverse cardiac remodeling. However, the specific functions of the CaMKII isoforms and splice variants in ischemia/reperfusion (I/R) injury have not been investigated yet. Thus, we studied...
ORGANISM(S): Mus musculus 
2014-09-08 | E-GEOD-58486 | biostudies-arrayexpress
UnknownAbstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.
Not available
S-EPMC5435609 | biostudies-literature
UnknownEtiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease.
Not available
S-EPMC10580156 | biostudies-literature
UnknownDeep learning enhanced ALPS reveals genetic and environmental factors of brain glymphatic function.
Not available
S-EPMC12878677 | biostudies-literature
UnknownMetformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.
Not available
S-EPMC12303861 | biostudies-literature
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