Sort   by:  
 Page size 
MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
TranscriptomicsZebrafish foxc1a is required for appendage specific neural circuit development
RNA-seq analysis of zebrafish foxc1a mutant For RNA-seq, mRNA was extracted from 38-40 hpf old embryos. We isolated wild type and foxc1a mutant samples by dissecting the entire first 6 anterior somitic segments (AS) through which the fin nerves migrate, and the adjacent posterior segments (PS; segme...
ORGANISM(S): Danio rerio 
2015-03-05 | E-GEOD-64125 | biostudies-arrayexpress
TranscriptomicsA circadian gene expression atlas in mammals assayed by RNA-seq
To characterize the role of the circadian clock in mouse physiology and behavior, we used RNA-seq and DNA arrays to quantify the transcriptomes of 12 mouse organs over time. We found 43% of all protein coding genes showed circadian rhythms in transcription somewhere in the body, largely in an organ-...
ORGANISM(S): Mus musculus 
2014-09-30 | E-GEOD-54651 | biostudies-arrayexpress
TranscriptomicsCircadian liver_wt and Clock mutants
One hundred ninety wildtype male C57BL/6J mice age 7-10 weeks were purchased from Jackson Laboratory and entrained to a 12:12 light:dark cycle for 2 weeks. Mice were placed in light-tight boxes on a 12:12 LD cycle for 4 weeks, then released into constant darkness. Starting 30 hours after entry into ...
ORGANISM(S): Mus musculus 
2010-06-11 | E-GEOD-3748 | biostudies-arrayexpress
TranscriptomicsLarge-scale analysis of the human transcriptome - Novartis dataset
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments have focused on specific biological processes and perturbations. Here, we have generated and analyzed ...
ORGANISM(S): Homo sapiens 
2002-12-06 | E-GEOD-96 | biostudies-arrayexpress
UnknownGenome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues.
Not available
S-EPMC555478 | biostudies-literature
UnknownThe transcription factor encyclopedia.
Not available
S-EPMC3439975 | biostudies-literature
Sort   by:  
 Page size