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UnknownAdaptive Use of Co-Data Through Empirical Bayes for Bayesian Additive Regression Trees.
Not available
S-EPMC11834989 | biostudies-literature
TranscriptomicsOverexpression of miR-155 enhances B-cell lymphoma growth by targeting TBRG1
MYC regulates the expression of multiple microRNA (miRNA) genes and defines the Burkitt lymphoma (BL) miRNA signature. Here, we investigate the role of the MYC-regulated miRNAs by gain- and loss-of-function analysis. Overexpression of 5 miRNAs that were significantly downregulated by MYC resulted in...
ORGANISM(S): Homo sapiens 
2015-02-20 | E-GEOD-64484 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lungs of C3H mice infected with Bordetella and mock control
Transcriptional responses in lungs of C3H mice infected with Bordetella and mock control
ORGANISM(S): Mus musculus 
2007-05-11 | E-TABM-266 | biostudies-arrayexpress
TranscriptomicsCell host-response to infection with novel human coronavirus EMC predict potential antivirals and important differences with SARS-coronavirus.
Differential expression was determined in Calu-3 cells between mock infected and infection with either Human coronavirus EMC and SARS coronavirus at different times post infection. Calu-3 2B4 cells were infected with Human Coronavirus EMC 2012 (HCoV-EMC) or mock infected. Samples were collected 0, ...
ORGANISM(S): Homo sapiens 
2013-05-03 | E-GEOD-45042 | biostudies-arrayexpress
UnknownVariation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study.
Not available
S-EPMC6407836 | biostudies-literature
TranscriptomicsCytokine stimulation systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates.
Background: The recent emergence of a novel coronavirus in the Middle East (designated MERS-CoV) is a reminder of the zoonotic potential of coronaviruses and the severe disease these etiologic agents can cause in humans. Clinical features of Middle East respiratory syndrome (MERS) include severe acu...
ORGANISM(S): Homo sapiens 
2014-08-31 | E-GEOD-56677 | biostudies-arrayexpress
TranscriptomicsCD40-mediated amplification of local immunity by keratinocytes in impaired by HPV
The interaction between the transmembrane glycoprotein surface receptor CD40 expressed by skin keratinocytes (KCs) and its T cell-expressed ligand CD154 was suggested to exacerbate inflammatory skin diseases. However, the full spectrum of CD40-mediated effects by KCs underlying this observation is u...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-54181 | biostudies-arrayexpress
TranscriptomicsStereo-seq analysis of human multiple sclerosis white matter lesions
Fresh frozen samples from human white matter MS lesions. Using Stereo-seq we compared mixed active/inactive lesions with lipid-laden foamy microglia with lesions containing ramified microglia. Study includes post-mortem subcortical white matter (WM) tissue of n = 7 donors with MS (5 females, 2 male...
ORGANISM(S): Homo sapiens 
2026-05-11 | E-MTAB-17040 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of arabinose fermentation by engineered Saccharomyces cerevisiae
Saccharomyces cerevisiae IMS0002 which, after metabolic and evolutionary engineering, ferments the pentose sugar arabinose. Glucose and arabinose-limited anaerobic chemostat cultures of IMS0002 and its non-evolved ancestor IMS0001 were subjected to transcriptome analysis to identify key genetic chan...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-01 | E-GEOD-27539 | biostudies-arrayexpress
TranscriptomicsKupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity.
Kupffer cells have been implicated in the pathogenesis of various liver diseases. However, their involvement in metabolic disorders of the liver, including fatty liver disease, remains unclear. The present study sought to determine the impact of Kupffer cells on hepatic triglyceride storage and to e...
ORGANISM(S): Mus musculus 
2011-10-17 | E-GEOD-33044 | biostudies-arrayexpress
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