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ProteomicsiTF Microglia Cell-Surface Proteomics
To elucidate the impact of Aβ pathology on microglia in Alzheimer’s disease pathogenesis, we profiled the microglia surfaceome following treatment with Aβ fibrils. Our findings reveal that Aβ-associated human microglia upregulate Glypican 4 (GPC4), a GPI-anchored heparan sulfate proteoglycan (HSPG)....
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD060977 | Pride
Lipopolysaccharide Ipsc microglia Amyloid-beta Surfaceomics Wga-hrp 
UnknownGenomics of Environmental Salmonella: Engaging Students in the Microbiology and Bioinformatics of Foodborne Pathogens.
Not available
S-EPMC8100199 | biostudies-literature
UnknownOptimizing Gait Outcomes in Parkinson's Disease: The Effects of Musical Groove and Familiarity.
Not available
S-EPMC12467459 | biostudies-literature
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
UnknownEvolution of the Human Cytokine Response from Acute Illness to Disease Resolution in SARS-Cov-2 Infection-Implications for Therapeutic Monitoring and Therapeutic Targets.
Not available
S-EPMC8051826 | biostudies-literature
UnknownInternational Network of Antibiotic Allergy Nations (iNAAN): Protocol for a type 2 hybrid effectiveness-implementation multicentre prospective cohort and target trial emulation study evaluating penicillin allergy delabeling via direct oral challenge.
Not available
S-EPMC12412947 | biostudies-literature
UnknownAre NKT cells a useful predictor of COVID-19 severity?
Not available
S-EPMC8768020 | biostudies-literature
UnknownTrajectories of re-engagement: factors and mechanisms enabling patient return to HIV care in Zambia.
Not available
S-EPMC9958345 | biostudies-literature
MetabolomicshRUV: Hierarchical approach to removal of unwanted variation for large-scale metabolomics data
Liquid chromatography-mass spectrometry-based metabolomics studies are increasingly applied to large population cohorts, which run for several weeks or even years in data acquisition. This inevitably introduces unwanted intra- and inter-batch variations over time that can overshadow true biological ...
2021-07-05 | MTBLS2483 | MetaboLights
UnknownCOVID-MATCH65-A prospectively derived clinical decision rule for severe acute respiratory syndrome coronavirus 2.
Not available
S-EPMC7725390 | biostudies-literature
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