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ProteomicsiTF Microglia Cell-Surface Proteomics
To elucidate the impact of Aβ pathology on microglia in Alzheimer’s disease pathogenesis, we profiled the microglia surfaceome following treatment with Aβ fibrils. Our findings reveal that Aβ-associated human microglia upregulate Glypican 4 (GPC4), a GPI-anchored heparan sulfate proteoglycan (HSPG)....
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD060977 | Pride
Lipopolysaccharide Ipsc microglia Amyloid-beta Surfaceomics Wga-hrp 
UnknownNeural Tracing Protein-Functionalized Nanoparticles Capable of Fast Retrograde Axonal Transport in Live Neurons.
Not available
S-EPMC11427170 | biostudies-literature
UnknownCell-surface tethered promiscuous biotinylators enable comparative small-scale surface proteomic analysis of human extracellular vesicles and cells.
Not available
S-EPMC8983049 | biostudies-literature
UnknownDiaphragmatic recovery in rats with cervical spinal cord injury induced by a theophylline nanoconjugate: Challenges for clinical use.
Not available
S-EPMC6830233 | biostudies-literature
UnknownMicroscaled Cell Surface Proteomics for Cryo-preserved Cells and Tissue Samples.
Not available
S-EPMC12338646 | biostudies-literature
ProteomicsMicroscaled Cell Surface Proteomics for Cryo-preserved Cells and Tissue Samples
Cell surface proteins (CSPs) regulate key cellular functions and represent valuable targets for diagnostics and therapeutics. Despite advances in proteomic workflows, CSP analysis from cryopreserved or low-input clinical samples remains limited by technical constraints, including reduced membrane in...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-07-30 | MSV000098694 | MassIVE
ProteomicsDiscovery and development of CLL-1 as a cellular immunotherapy target in juvenile myelomonocytic leukemia
Juvenile myelomonocytic leukemia (JMML) is an aggressive hematologic malignancy with myeloproliferative characteristics that affects young children and is associated with significant morbidity and mortality. Leukemia stem cells (LSCs) have been shown to drive relapse and progression in JMML and incl...
ORGANISM(S): Homo sapiens (Human) 
2025-02-03 | PXD052910 | Pride
Jmml Surfaceomics Car-t cell Immunotherapy 
UnknownHuman platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5.
Not available
S-EPMC9298447 | biostudies-literature
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