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TranscriptomicsNovel aspects of the transcriptional stress response in the paraventricular nucleus of the mouse strains DBA/2J and C57BL/6J
The pivotal role of stress in the precipitation of psychiatric diseases is generally accepted. To further elucidate the underlying molecular mechanisms, gene networks and signalling cascades, we investigated the impact of an acute stressor, forced swimming, on the gene expression profile in the hypo...
ORGANISM(S): Mus musculus 
2010-10-20 | E-GEOD-20877 | biostudies-arrayexpress
TranscriptomicsAllele-specific FKBP5 DNA demethylation: a molecular mediator of gene-childhood trauma interactions
While the paradigm that genetic predisposition and environmental exposures interact to shape development and function of the human brain and ultimately the risk of psychiatric disorders has drawn wide interest, the corresponding molecular mechanisms have not been elucidated yet. Here we show that a ...
ORGANISM(S): Homo sapiens 
2012-11-03 | E-GEOD-42002 | biostudies-arrayexpress
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