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UnknownIdentification of novel genes involved in long-chain n-alkane degradation by Acinetobacter sp. strain DSM 17874.
Not available
S-EPMC1907095 | biostudies-literature
UnknownDisruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects.
Not available
S-EPMC124907 | biostudies-literature
MetabolomicsSerum protein N-glycosylation changes in multiple myeloma

BACKGROUND: Multiple myeloma is characterized by clonal proliferation of malignant plasma cells in the bone marrow that produce monoclonal immunoglobulins. N-glycosylation changes of these monoclonal immunoglobulins have been reported in multiple myeloma, but previous studies on...

2022-04-27 | MTBLS676 | MetaboLights
TranscriptomicsEffects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: a Randomized Double-blind Placebo-controlled Trial
The gut microbiota has been implicated in obesity and cardiometabolic diseases, although evidence in humans is scarce. We investigated how gut microbiota manipulation by antibiotics (7-day administration of amoxicillin, vancomycin, or placebo) affects host metabolism in 57 obese, prediabetic men. Va...
ORGANISM(S): Homo sapiens 
2016-07-15 | E-GEOD-76003 | biostudies-arrayexpress
MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
UnknownEffects of a cluster randomized controlled kindergarten-based intervention trial on vegetable consumption among Norwegian 3-5-year-olds: the BRA-study.
Not available
S-EPMC6692927 | biostudies-literature
TranscriptomicsRNA-seq of livers from mice treated for eight weeks with the glucagon receptor antibody, REGN1193, compared to mice treated with a control antibody, REGN1945, (control group)
Chronic glucagon receptor inhibition with a glucagon receptor antibody decreases amino acid catabolism and ureagenesis, while increasing plasma triglyceride concentrations, plasma very-low density lipoprotein cholesterol concentrations, and liver triglyceride concentrations. To dissect the molecular...
ORGANISM(S): Mus musculus 
2022-10-09 | E-MTAB-12048 | biostudies-arrayexpress
TranscriptomicsGenome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA
To determine the global effects of ASCT2 inhibition, we used next generation sequencing to determine mRNA expression changes in PC-3 cells treated with BenSer or GPNA for 48 h. Examination of two different ASCT2 inhibitors BenSer and GPNA in prostate cancer cell line PC-3.
ORGANISM(S): Homo sapiens 
2015-04-10 | E-GEOD-65112 | biostudies-arrayexpress
TranscriptomicsGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Differentiation of hemopoietic stem cells into granulocytes is characterized by distinct changes in the transcriptome. We analyzed mRNA expression in primary murine myeloid cells at four successive stages of hemopoietic differentiation; Lin- Sca1+ cKit+ stem/progenitor cells (LSKs), promyelocytes, m...
ORGANISM(S): Mus musculus 
2014-05-14 | E-GEOD-57622 | biostudies-arrayexpress
ProteomicsN-glycomic signature of stage II colorectal cancer and its association with the tumor microenvironment
The choice for adjuvant chemotherapy in stage II colorectal cancer (CRC) is controversial as many patients are cured by surgery alone and it is difficult to identify patients with high-risk of recurrence of the disease. There is a need for better stratification of this group of patients. Mass spectr...
ORGANISM(S): Homo sapiens (Human) 
2020-10-21 | PXD021682 | Pride
Mass spectrometry imaging Glycomic Colorectal cancer 
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