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MetabolomicsEvolutionary novelty of Apolipoprotein D facilitates metabolic plasticity in lepidopteran wing

Understanding metabolic plasticity of animal evolution is a fundamental challenge in evolutionary biology. Owing to the diversification of insect wing morphology and dynamic energy requirements, the molecular adaptation mechanisms underlying the metabolic pathways in wing evolution remain largely...

2026-03-29 | MTBLS4308 | MetaboLights
MetabolomicsEvolutionary novelty of Apolipoprotein D facilitates metabolic plasticity in lepidopteran wings

Understanding metabolic plasticity of animal evolution is a fundamental challenge in evolutionary biology. Owing to the diversification of insect wing morphology and dynamic energy requirements, the molecular adaptation mechanisms underlying the metabolic pathways in wing evolution remain largely...

2026-03-29 | MTBLS11285 | MetaboLights
Proteomicsprotein turnover during homeostatic plasticity
Using quantitative proteomics we identified group of synaptic genes with decreased protein synthesis during homeostatic plasticity. To obtain further information about their mRNA levels/sequences (3’UTR) we performed polyA RNAseq. Using EISA analysis of Ribominus RNAseq dataset we could further diff...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-04-05 | PXD004150 | Pride
Neuron silac homeostatic plasticity 
GenomicsNatural Killer Cell Plasticity During IL-15-driven Homeostatic Proliferation
Here we performed single-cell RNA sequencing to address repertoire stability and subset plasticity during IL-15 driven homeostatic proliferation. Sorted NK cell subsets representing discrete stages of NK cell differentiation are compared with the corresponding subsets after proliferation and further...
EGAS00001003946 | EGA
ProteomicsNascent Proteome Remodeling following Homeostatic Scaling at Hippocampal Synapses.
Neuronal networks are subject to fluctuations in both the magnitude and frequency of inputs, requiring plasticity mechanisms to stabilize network activity. Homeostatic synaptic scaling is a form of synaptic plasticity that adjusts the strength of neuronal connections up or down in response to large ...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-12-22 | PXD004889 | Pride
Synaptic plasticity Q exactive plus Homeostatic scaling Lfq 
Proteomicscompartmentalized protein expression in rat hippocampal neurons undergoing homeostatic plasticity
Synaptic scaling is a form of homeostatic plasticity which allows neurons to adjust their action potential firing rate in response to chronic alterations in neural activity. Synaptic scaling requires profound changes in gene expression, but the relative contribution of local and cell-wide mechanisms...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-07-09 | PXD020745 | Pride
Neurons Stimulation Homeostatic plasticity Hippocampus Rat Cellculture Ptx Dendrites 
GenomicsIntrinsic Homeostatic Plasticity in Mouse and Human Sensory Neurons
Intrinsic Homeostatic Plasticity in Mouse and Human Sensory Neurons
PRJNA989045 | ENA
UnknownMicroRNA regulation of homeostatic synaptic plasticity.
Not available
S-EPMC3136313 | biostudies-literature
GenomicsAstrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus
Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus
PRJNA678677 | ENA
ProteomicsNeuronal proteome dynamics during homeostatic scaling.
Homeostatic scaling adjusts synaptic strength in response to persistent changes in neuronal network activity. This compensatory mechanism requires proteome remodeling accomplished via regulation of protein synthesis as well as degradation, but the global patterns of proteome remodeling and the under...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-03-31 | PXD016004 | Pride
Synaptic plasticity Proteome turnover Dynamic silac Proteome remodelling Homeostatic scaling 
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